You gotta admit the ergot wine stories are very intriguing. The story from Todd and Krystal above is a real trip. Fermentation and what not, there's some very interesting things going on. Thanks for the report as well Jon.
Just wanted to say excellent thread everyone...I knew about the bluelight study, and glad the study is being analyzed by the forum members here and all the contributions made in this thread. I'm going to go back and read this thread from from beginning to end.
Why all of the psychedelic researchers of the past have overlooked the fact that "mint" was an ingredient in the kykeon brew is beyond me. Heck, no one has even bothered to drink a cold water extraction of infected barley, however a guy on the entheogen.com forum did just that a couple years ago and tripped his brains out, seeing full on open-eyed hallucinations. Jonathan Ott was going to do just that, but chickened out at the very last minute.
This author below from the entheogen.com forum did the ICE cold CWE of infected wild barley (with some wheat/rye mixed in it?) found in the pacific northwest under the mountain known as Tahoma. Author claims 1.75 grams of claviceps purpurea was ground up under low light conditions (starlight), soaked for 3.5 hours in ICE cold water in the fridge, filtered through a very thin paper filter, with the ending 6 oz hypothetically consumed. I have more to say on this at the end of this thread reply by giving the experimental results of Peter Webster's experiments on converting ergotamine, ergotamine as you may recall is the principal toxic ergopeptine alkaloid in ergot that can be converted to ergine (LSA) with basification. Anyhow, Peter converted the contents of his prescription Gynergen tablets, which is 1mg of ergotamine tartrate each, to ergine/iso-ergine (LSA, iso-ergine) in a basified solution, the solution which Peter believes is very psychoactive once it is allowed to form the 3 drug conformations (d-boat LSA, d-chair LSA, and iso-chair LSA) over the course of an hour or more in solution. His Gynergen tablets (consisting of ergotamine) are not psychoactive at all in amounts even up to 5mg he said, but once he dissolved them into a solution basifying them first (using wood ash as the priests may have used), then adding ascorbic acid to make the freebase forms of the 3-conformations of the drug more bio-available in salt form, he experienced definate strong psychoactive effects. His trial consisted of consuming about 1200 micrograms of ergine-isoergine (LSA, iso-LSA) mixture. His experiment in Mexico where he consumed about 10mg of prepared morning glory solution was the equivalent of high dose LSD he stated. He speculates that if he were to consume an even higher dosage of ergotamine in solution (beyond 1200mg of the lsa/iso-lsa mixture) that it might actually approach the level of his past 10mg morning glory solution experience.
Author from entheogen.com forum experience with cold water extraction of 1.75g ergot:
SOTC describes the experience as being similar to, though visually far more intense then HBWR or MG, Complex geometry overlayed on backgound of colors, constantly changing like a tapistry, intermixed with very bright flashes of light (bubbles) and on ocassions beams of light. He describes the mental effects aside from that, and the auditory perceptions as being more or less lucid, which is what surprised him more than anything. This was barnone the most visual experience of the feline's life, and he had, in the course of wandering fields, consumed hefty dosages of 'godflesh' in times past, one species in particular noted for vivid visions, the feline found this to be far more intense.
I was the one that started the whole mess about the acetaldehyde and lsa stuff...based on a crude interpretation of the study I accidentally found below when cruising the net:
see Adducts_paper attached (which Jon posted in the beginning of this thread)
If you want to see a picture of the lysergic acid hydroxyethylamide molecule just look at the color photo in the middle of the book "LSD, my problem child" by Albert Hofmann. It looks very similar to LAE-32, which the people in a study found to be psychedelic at 1 to 2 mg, and was short lasting. A paragraph about LAE-32 is described in TIHKAL by Shulgin. It was not as strong as LSD, but still somewhat potent for a brief time nonetheless. The study participants still preferred the LSD over the LAE-32, they found LSD to be more therapeutic.
brief summary:
Reaction of Indole with Acetaldehyde. A 0.2% solution of indole in equal amounts of water, ethanol, and acetaldehyde formed a product with 60% yield after 1 hour of reaction at ambient temperature. Omitting the ethanol (50% acetaldehyde in water mixture) had no effect. Decreasing the concentration of acetaldehyde to 0.1% increased the reaction rate and percent yield of product.
For preparative purposes, a mixture containing 20mg of IAA in 0.5mL of 40% water/40% ethanol/20% acetaldehyde was allowed to react at ambient temperature for 18 hours.
I'm not going to go into the whole adducts thing, as others here have gone into much depth, but will state that it gives a short lasting psychedelic state that does not seem to last as long as the normal morning glory extraction. The preparation in peppermint and everclear causes a state that comes on quick and feels much stronger than a normal preparation, but is too short lasting for me to really enjoy....perhaps taking a larger dose would overcome this. I still prefer the normal shamanic method in cold water without forming adducts or whatever with additional ingredients. But note that I have never taken a big dose of the adduct formed solution. It is definately strong when it comes on within 45 minutes, no messing around, and stays at that level for a couple to a few hours at a low dose...there could be much potential to this with experimentation, if someone were to get the experimental conditions just right. I'm going to have to look into Jon's wine experiments, sounds really good.
Why fresh morning glory extracts seem to work when prepared in a cold water solution and allowed to sit several hours (the same method used by the shamans)...is explained below by Webster...I had also briefly chatted with him on-line a long time ago, and he sent a link to his paper that I have also attached from earthrites. this method (preparation in plain cold water with a dash of d,l tartaric acid powder mixed in to reach a ph of 3 to 4) caused the only two very fantastic psychedelic states that I myself have ever experienced from morning glory seeds, with no nausea. In the distant past, I had done in dreams literally hundreds of acid hits at all different doses, and I found the short lasting state induced by the seed solution to be compatible in many similar ways.
In the first experience, I took about 6 grams of fresh morning glory seeds that I bought from a vendor on-line, crushed them inbetween two paper plates on a concrete floor with a hammer, then took the dust and added it to a coffee grinder and ground the seeds to a very fine dust, I then poured the dust into two large family sized lipton tea bags and stapled them shut. By the way, this is the same method used by "Hermes" from the old Lycaeum forum, he had lots and lots of very strong psychedelic experiences with this tea bag method, and let us not forget that the Shamans would also hammer the seeds and place them into a loin cloth and soak it in water for a time.
Hermes mentioned that the seeds needed to be less than a year old, and preferably the fresher the better, forget about using old seeds. Hermes used to prepare a lemon juice acidified cold water solution (using the empty tea bag method) of the Martha Stewart labeled heavenly blue morning glory seeds from K-mart. He would put on his headphones, lay back and close his eyes and very detailed visuals would develop that would intensify with the music he heard. He mentioned the music would sound just heavenly and broke out into tears from the experience once it was so beautiful.
I then poked a hole into a lid on a large mason jar and attached the tea bag strings to the hole on the lid and secured the hole with a square of duct tape. I then filled the mason jar with distilled water and a dash of d,l tartaric acid (easy to find on-line, used for wine making) to bring the ph to 3.5 (checked ph with a calibrated electronic ph meter)....then placed the mason jar with the tea bags floating in it in a fridge on a portable battery powered magnetic stirrer and let the water spin in the jar for several hours at high speed, it was all kept dark in the fridge. After several hours, I opened the jar and squeezed any juice out of the tea bags back into the water by pressing against the tea bags and the side of the jars with a large spoon, I then threw the tea bags away, and put the lid back on and allowed the contents of the jar to spin overnight on the magnetic stirrer in the fridge, again entirely dark. I wrapped foil around the jar to ensure that it was light proof when opening and closing the fridge door.
The next day I drank 1/2 of the solution, and then went to a shopping mall with my sp and about 2 to 2.5 hours after I had drank the solution I was feeling a very strong and most enjoyable psychedelic trip from the seeds, note that it does take a couple to several hours before you feel the effects of properly prepared morning glory seeds, the music in all the stores I walked into just sounded sublime, and very much enhanced, I was incredibly euphoric the whole time and could not believe how the music had sounded so much better for hours, the trip began to subside about 3 hours after it began. I also had incredible visual enhancement, it was a most enjoyable psychedelic state. The psychedelic state caused by the seeds is very euphoric and imho it would be very difficult to have a bad time on properly prepared seed solution. It seems to accentuate the positives and doesn't even allow negative mindstates to even begin to form, so in some ways it may be different from typical psychedelics.
This particular positive based psychedelic mind state would be perfect to use in the pavilion where the Eleusis ceremony took place for 2000 years in ancient Greece, in that ceremony it is theorized that inititates all were given a powerful psychedelic brew to drink (prepared by the priest) as there would be hundreds of new "initiates" in the hall taking a psychedelic for the very first time...if you think about it, you would want them to take a psychedelic which is low on the spectrum of causing "freak outs", you wouldn't want a person in there having a bad trip and freaking all the others out would you? A cold water extraction prepared from the nearby growing infected paspali grass would have the same alkaloid profile as morning glory seeds. Or, doing a cold water extraction on claviceps paspali from the infected barley grains growing would cause only the good water soluble psychedelic alkaloids to absorb into the water while leaving the poisonous non-water solubles behind. It is known that Plato attended the ceremony and when he had visions there, it is postulated that is how he came about with the Perennial Philosophy. You can read more about the Perennial philosophy from Aldous Huxley. Lots of well known famous Greek intellectuals attended the Ceremony at Eleusis and drank the brew. We know from the written hymns that the brew was composed of a solution of
barley grains and
mint. You never know, but some kind of maoi acting plant may have been added as well to further strengthen the psychedelic effects. The brew was kept a secret by the priest who handed it down to the priest in charge for some 2000 years. At one time, the sacred brew was leaked to a handful of Greek people who used it at a party and in doing so, they "profaned" the sacred brew. Death was the punishment for consuming the brew outside the ceremony or even talking about it could lead to a death sentence.
Report from a friend who is very experienced with ayahuasca:
Just wanted to thank you for the Morning Glory thread. Yesterday I had my first experience with this Green Elder with a cold water extraction in phosphoric acid, pH 3. I shook my little muslin spice bag 4 times in the hour, filtered crudely through coffee filters and Kleenex, then put it back in the fridge until the next day. I used 8g. of "Ipomoea tricolor" from ******** **** , and the experience was wonderful. I had 1g. of raw rue seed 2 hours before, taken in yogurt so I wouldn't have to chew them or taste them. The experience lasted from 11am to 6pm, with a distinct afterglow period where I was totally baseline, but I was still full of energy. I wish I had explored CEV's more, but I got some impressive visions that were totally unlike anything I'd seen in Ayahuasca , and more like the paintings of Dali or Magritte (for example, a pyramid with an eye in the center floating on clouds was something I saw).
Unlike Ayahuasca , this WAS NOT SCARY at all and felt really nice in the body, and was easy on the mind.
Please read how you've inspired me! See the Plant World Forum: Yopo/Vilca as Medicinal Herbs. The cold water extraction seems to be generalizable to seeds with nasty seed oils, such as yopo and Syrian rue.
When I made Syrian rue with cold water methods, the liquid (which usually makes me retch just smelling or tasting it) comes out clear of any rue smell or taste, which all stays in the bag. I used a muslin spiced bag with a coffee filter folded up inside it containing the ground seeds.
Not only has the LSA thread revolutionized LSA prep, but also can make Syrian rue and yopo more user friendly...
One hour, shaken every 15 minutes, filtered with plain old coffee filters and Kleenex. Kept in the fridge until the next day. He smoked mapacho and caapi leaves from time to time and found the experience *very* interesting, lasting for 6 hours. Eyes closed visions (not just visuals, but fully-formed visions) were nothing like he had ever seen before with Ayahuasca -- totally different. He saw lots of the "eye" motif, with an eye in a pyramid against a brilliant blue sky and floating on clouds. He also had a lucid dream in which a phosphorescent snake encouraged him to try to follow him through a portal in the corner of his bedroom, but the snake slithered through, while he, the lucid dreamer, couldn't figure out how to perform the same trick. The 6-hour period was followed by another 5 of afterglow, and it continued, he said, into the next day very strongly.
He had no nausea of any kind, and no sedation from Heavenly Blues (Ipomoea triclor). He told me it felt very much like being sped up on lots of caffeine or Kratom . The day was very full and active, as opposed to meditative and serene at home, as with aya. He went all over town, cleaned house, did things he had postponed for months at home in the way of repairs and cleaning...l
A word of warning! I only drank 1/3 of the portion and got effects similar to yours one hour later. He thought it was a dud, and went to the store, and it hit him while he was standing in the checkout line of the supermarket. He said the body effects made it difficult not to just drop everything and start dancing and singing! He had another 1/3 two hours later, and the last 1/3 two hours after that. The visions came more or less later in the experience, but the body effects came early on. Effects were not sedating at any time. He was relaxed and super energetic.
It's hard to just lie down and achieve CEV's because it's difficult to remain still and calm in the beginning. CEV-observation is more conducive towards the end of the experience, he said, unless you especially adept at sitting or lying still long enough to trance into the CEV state amidst the excitement, which makes one want to dance around and sing!
Imho, the combination of properly prepared morning glory extracts combined with caapi/harmine hcl/thh should seriously be explored more, this is the way to go.
Hermes:
Depending on seed quality, you should get some weak to decent effects from 8 grams, like mild reality bending, marked enhancement of aesthetic perception, insights, weak open eye visuals, moderate but subtle closed eye visuals (especially with music). I find that more satisfactory results are achieved with more seeds, like 14 grams or more. This much is needed to enter truly psychedelic territory. I wouldn't recommend this much if you haven't tried lower doses with the same seeds and method, however. LSA can cause significant vasoconstriction, causing restricted blood circulation to extremities. Make sure that your toes don't get numb or tingly on 8 or so grams first. And don't mix with other vasoconstrictives, like ephedrine or caffiene.
I usually just measure by Burpee bags. These are 1.8 grams each. I have used anything ranging from 3 to 12 of these. Strangely, the 12 bag trip was relatively weak. They must have been some old seeds. My strongest experience ever with MG seeds was with the Martha Stewart brand from K-Mart.
I had strong 4D lattice-like open eye visuals and warping and melting of furniture with only 400 seeds. There are about 32-36 seeds to a gram. The Martha Stewarts are more expensive than the Burpees. They are like $1.30 a bag or something close to that for a 1.2 gram bag. The Burpees are something like $0.88 a bag and each bag has 1.8 grams. That's $2.05 a gram for Martha Stewart seeds and $0.92 a gram for Burpee seeds. It seems to be a trade off.
My favorite way to go about this is to first wash the whole seeds in a bowl with a little water and a very small amount of liquid handsoap. I slosh them around and rub them a bit in the soapy water (not too long--could reduce potency). I then rinse them good with cold water in one of those screen vegetable strainers. This is intended to wash off any fungicide or other adulterants. I then dry the seeds well with paper towels. Then I grind the seeds in coffee grinder to a fairly fine consistency, but not to the point of being powder. The hulls should remain somewhat course, while the lighter colored inner stuff is pretty much powder. I then put this stuff into one or several empty tea bags. Don't overfill one. If the bags are small, use several. Next, put the bag(s) into a full glass of cold distilled water and use a spoon to press on them and make sure they are well-saturated with water. Let sit for 10 minutes in a cool dark place. Use spoon to squeeze and agitate the bag against side of glass some more to get more stuff out. Don't press too hard or you will break the bag and get seed mush into the water, which is undesireable. Leave for 10 more minutes. Squeeze again. Leave for 10 minutes. Squeeze. Remove bags after squeezing most of the water from them into the glass. You can suck on the bags if you want to get more stuff. I don't generally do this. Discard bags. Drink water. Get yourself into the mood with some good music and wait for effects. You might want to take a little ginger if you are worried about nausea. Usually I don't get any, but sometimes there is a little, probably partly from pre-trip anticipation anxiety.
For me, they seem to be similar in both duration and effect. The only real difference I notice is that LSA is a little more lethargic, at least in the early phase of the trip. LSD is a bit more speedy. With LSA, I am much more able to lay around or focus on one task like painting. I also noticed that it is possible to go to sleep while still tripping on LSA, which is impossible with LSD. I slept once on LSA and had incredibly visual dreams! These were the most beautiful visuals I have ever seen under any circumstances. I dreamt that I was being shown the entire unfoldment of the universe, with the evolution of man, and it was all represented on this incredible spinning wheel. It was indescribable. I want to go to sleep on LSA again and attempt to have a lucid dream. That would be nothing short of amazing!
Anyway, my LSA trips last 10-12 hours or so, with slight effects that linger for another 24 hours or so. And I usually feel something like an afterglow for a week or so afterwards. During this period, I am much more creative than usual and happier too. I also notice that colors look slightly more pronounced for a week or so in a very LSA specific way. I never noticed this on LSD.
Comfortably_Numb asked where I buy my seeds from. K-mart and Wal Mart have been typical sources. The most powerful brand of seeds that I ever tried were the Martha Stewart brand from K-Mart (I had strong effects, with good open eye visuals, on only 300 seeds! I used a water extraction with some added lemon juice on this occasion. I do not know if this helped). Burpee seeds work well too, but didn't seem as potent as the Martha Stewart brand. The Burpee seeds are less expensive. I have never tried bulk seeds. As far as I know, the ones that I tried didn't have any pesticides. Nothing was mentioned on the package that would indicate this. I did always wash the seeds just in case, however.
If anyone tries this, inform us about the results. Tell me if the tea-bag method worked for you.
If the taste bothers you, you can add something to the water, but I wouldn't guarantee that it will not reduce potency. The taste isn't that bad. Just drink it fast.
What is it with eyes anyhow? Does anyone else see eyes filling their CEVs or OEVs? I see eyes, eyes in triangles, wings, eyes in triangles with wings, cherubim, seraphim, pyramids, pyramids with wings and eyes and caducea, utchats, lions, owls, cobras, and generally anything related to the Western Mystery Tradition. The first great "vision" I saw was while on Morning Glories and listening to Mozart's Requiem. When the Lacrimosa began, I saw incredible Angelic forms and felt this incredible awe and love for existence. I think I stole a glimpse of the Beautific Vision itself. I cried and sobbed for hours, in pure ecstacy. I knew, however, that I only encountered the very periphery of the "Inner Kingdom," since the cherubs revealed neither their hands nor their faces, just three pairs of wings. I had never seen them before this, in religious paintings or otherwise. I had not read the bible or anything before this had happened. Afterwards, upon doing a bit of research, I saw that they are commonly encountered by mystics of various cultures, especially in the West. In particular, I saw them in a book on Islamic architecture, painted on the ceiling of a Mosque. These looked incredibly similar to those I saw, only very washed out and a far cry from the real thing. These things just can't be painted. They have to be experienced.
So, what sort of comparison would you now make between LSD and LSA? In my experience, they are difficult to tell apart. The taste in my mouth and the physical energy level are the only things that seem different. LSD causes a "taste hallucination" that resembles rusty iron, while LSA causes a taste somewhat like bee pollen. Also, LSA has a much more lethargic feel, at least in the early portion of the trip. Other than that, they are the same for me. Really, it seems like LSA is a little more visual for me for a given amount of mind alteration.
It always seems to me that with LSA, the highly visual phase is late in the session, long after body phase and introspective phase. I wonder if the occipital lobe (visual cortex if I am not mistaken) of the brain is one of the last regions of the brain through which the blood passes.
in fact, I have experimented with this combo (cold tea from 800 MG seeds + 50mg ephedrine) before and it made my extremites go very nearly totally numb. I had lots of intense tingling in my hands and feet, as if they had gone to sleep. During part of the experience, I actually had pretty significant pain in the veins in my hands. Besides, I noticed that for some strange reason, the ephedrine seemed to diminish the desired effects of the LSA. Really, ephedrine is a nasty drug no matter how you use it.
It seems to me that you will get less lethargy and nausea if you perform the water extraction and get a purer product. Those nasty nonpolar compounds seem to contribute a great deal to the lethargy, nausea, headache, tunnel-vision, etc. With a good water extraction, I get none of that.
As for visuals, I can't even begin to describe most of them. And my memory of them is likely not very accurate since it has been a few years. I tend to translate the experiences into a form that I can remember, as the real thing cannot be represented with sober thought. The visuals are beyond representation for the most part. All that I can give you are general themes.
I tended to see what seemed to be a four-dimensional lattice structure that appeared to be "behind" things, as if everyday reality were just a bright projection that obscured the real luminous hyperspatial structure behind it. Things tended to have eyes and feathers on them. Often what dominated the visuals was a winged eye in the center of my vision. Often, instead of wings, the eye was surrounded by colorful mandalic geometric forms or organic patterns like vegetation. But it was very common to see a serene eye in the focal point of my visual field with all sorts of fantastic forms radiating from it.
I also saw lots of angelic forms and gothic celestial architecture, particularly when listening to Mozart's Requiem on god headphones while tripping with my eyes closed.
I saw a vision of a pyramid, floating in the air, with the Eye of Ra on it, and with a sword piercing it from beneath. The sword was entwined with two cobras, as in a caduceus. And around this pyramid atop a snake entwined sword were four large luminous feathered wings, each one a distance out from each corner of the pyramid, coming from beneath the whole figure and reaching above it, almost as though the wings were guarding it. This whole figure has obvious occult meaning. I just wonder why the images are so typically Egyptian in character, at least for me.
I have found many things similar to my visions in the art of Alex Grey. The eyes all over things, the energy lattices, and so on, are all very similar to what I have seen. Have you seen Grey's painting called "Dying" ? That eye-filled vortex pattern is something that I have seen. It seemed to me at least while I was tripping that the winged eye that dominated things was my soul, maybe something like the "ba" of the Egyptians. I once saw it rising up to meet the light, as if I was underwater seeing the sun above the surface and my soul was flying up to join the sun.
I also once saw a great field of eggs, above which was a giant watchful eye, surveying the field of eggs. Some of the eggs were cracking, and the cracks were lined with peering eyes. Every exposed opening was filled with eyes. And I could see myself as one of these cracking eggs.
Another time, I saw myself as a red dragon, what seemed to be my true form in this hyperspace, flying up, seeking the Source.
All of the visuals have a quality that I can't describe well, verbally or with illustrations. Everything in that interior realm seems made of subtle energy and is luminous. It also often seems to have more than three spatial dimensions. It usually has a very detailed and very ordered structure, very mathematical, but arranged with a kind of structural harmony that is never seen in the physical world. The structures are beautiful beyond description. It is like visual music, with the sizes and positions shapes seemingly related by some kind of precise law that binds everything together in the most perfect harmony. The flawed forms of our world compared to those perfectly harmonious ones of that world are like the cacophany of a cocktail party compared to a symphony by Beethoven. Visual order like that has never been seen in physical form, in the natural world or in art. Fractal geometry sometimes resembles it, but still falls very short.
Peter Webster (from the book Sacred Mushrooms of the Goddess):
So, we have the possibility that ergine (LSA) can be in one of three states: it can be ergine in the chair or boat conformations, or it can be isoergine in the chair conformations. And in many chemical and physical situations, the 3 forms are constantly converting themselves from one to the others, and achieving a typical equilibrium distribution. We therefore must consider that in an ergot preparation made according to our suggested method, and in morning glory seeds as prepared by Mesoamerican shamans, we are not dealing with pure chemically synthesized ergine or pure isoergine. Both pure compounds have been tested and found wanting by some investigators, including Dr. Hofmann.
The equilibrium mixture of ergine and isoergine may actually be the true psychoactive substance of the kykeon, and of ololiuhqui as well. Since ergine spontaneously changes to isoergine when in solution, over a period of perhaps several hours, any process to partially hydroluze the alkaloids of ergot such as our proposed recipe -- or even the Aztec ahaman's procedure for extracting ololiuhqui--should result in a mixture of the 3 states as represented here, (see photo of chemistry).
Chemist Peter Webster saids: Ingesting either ergine or isoergine as a pure compound, however, may not result in the equilibrium mixture arriving at brain receptors.
You know how with *dma, you don't feel "the magic" unless both the S and L isomer are present together and ingested at the same time...either one ingested on it's own will not cause the magic according to Shulgin. Even though those are isomers, and we are dealing with conformations here instead with LSA, maybe Peter is on the right track with all this 3 conformation to feel the magic stuff ? who knows.
Peter mentioned that a few milligrams of his MG syrup extract (A/b, A/b extracted?) glowed bright-blue Fluorescence...and was as powerful as high-dose LSD ... his extract producing "one of the most powerful psychedelic experiences I had known" (Sacred Mushrooms of the Goddess, March 2006).
First, he told lots of kids in Mexico where he was staying if they wanted to help him to go gather fresh morning glory seeds off the ground for him, and he would give them like a penny for each one they found, or something like that. He then extracted several kilos of seed using a simple process, purifying an alcoholic extract between organic solvents in the presence of ammonia and aqueous solutions of tartaric acid. After a couple days work, he obtained a nearly colorless syrup that exhibited the bright-blue fluorescence of active lysergic acid compounds.
This is how Peter made his very powerful extract:
.. The procedure involved extracting finely powdered Heavenly Blue Morning Glories w/ Ethanol. Most ethanol was evaporated off in a rotovap, added a bit more water, basified the messy solution w/ ammonia (to make sure alkaloids weren't in the salt form) & extracted 3x w/ dichloromethane, combined extracts were extracted with w/ water containing 5% tartaric acid. The alkaloidal-tartarate solution was basified w/ ammonia and extracted w/ dichloromethane. Evaporate DCM leaving a light coloured syrup that fluoresced bright blue under blacklight...
Sounds like a double A/B extract.
Here is where Peter's theory (with pictures and chemistry) is located on the 3 conformations formed in liquid solution after the solution (such as cold distilled water, etc.) is allowed to sit or stir for some time:
See pages 24--35 of the earthrite's journal:
"Secret Recipes - Hofmann Symposium, Peter Webster, Ground Breaking Work on The Kykeon Mystery - Edited by Peter Webster and RevMEO"
http://earthrites.org/invisible-college/IC-Beltane07sm.pdfPeter verified that his early on original wood ash kykeon hypothesis was correct by performing several experiments on his prescription migraine tablets Gynergen (each Gynergen consists of 1mg of ergotamine tartrate) since he did not have ergot available to him. He testified that for migraine relief, one can take even up to 5mg of the ergotamine and it would have no psychoactive effect. This fact provided a control on his experiments. He performed three trials, using first one ergotamine tablet, then 2 and then 3 tablets. Since ergotamine tartrate-the actual compound in these tablets--is a much larger, and therefore heavier, molecule than ergine (LSA), a simple calculation shows that converting 1mg of ergotamine will ideally yield only a maximum of 4/10ths of a milligram (400 micrograms) of ergine and isoergine in their equilibrium mixture in solution (Peter states that this equilibrium of LSA or ergine to it's 3 drug conformations, d-boat, d-chair, and iso-chair...takes around an hour or more to happen in solution).
In the first trial, he heated 1 tablet containing 1mg of ergotamine with 200mg of hardwood ash (like the priest may have used) in 20ml of vodka in a kitchen double-boiler after 1 hour the alcohol had boiled off. He continued to heat this mixture for 2 more hours at around 50 degree C (122 degree F), then neutralized the mixture with vitamin C (ascorbic acid). Decanting the liquid from the residue of solids left by the wood ash, he then drank the result. A definite, but weak, psychoactive effect was noticed.
He then repeated the experiment with 2 and then 3 migraine tablets, the result was stronger and left no doubt in his mind that the partial hydrolysis process he hypothesized does indeed happen to ergotamine.
There is little reason to believe that if the partial hydrolysis process occurs with the ergotamine in a Gynergen tablet that it would not occur with the ergotamine and other ergopeptines in ergot.
In his experiment, he used vodka as a solvent, since in a Gynergen tablet the ergotamine content exists as tiny crystals and an alcohol-water mixture would enhance the low solubility of these ergotamine crystals.
Neutralising would make the brew more palatable, and in addition augment the solubility of ergine/isoergine (LSA-iso LSA) in body fluids since these alkaloids easily form salts with acids such as ascorbic, tartaric or even hydrochloric. The salts are far more soluble than the freebase alkaloids.
He suggest that in addition, to fully confirm our hypothesis, assayed ergot should be used and chromatographic analysis used to determine the ideal conditions necessary for a complete partial hydrolysis to ergine (LSA), and for the equilibrium with isoergine (iso-LSA) to be established.
In his final tests, he used 3 ergotamine tablets. With 3 tablets, the effect was, of course, even stronger, although at that level it was still not nearly the equivalent of his trial of morning glory extract in Mexico (which he found comparable to high dose LSD). He believes that the dose he used on that trial was much higher, perhaps as much as 10mg, and of course, the ololiuhqui extract contained a minor amount of other, possibly, psychoactive agents.
With 3 converted ergotamine tablets--ideally producing 1200micrograms of ergine-isoergine mixture in solution, he found the effect came on quickly after only 20 minutes. He said the effect, however, was not at all the same as LSD or peyote, he found it was more hypnotic and inward than the typical psychedelic experience. The ergine - isoergine (lsa, iso-lsa) experience also seemed less dramatic to him, stating that it was more gentle and leads one to recline with eyes closed, whereupon mental processes seem kaleidoscopic and influenced strongly by set and setting.
He speculates that the experience may have well been just the type of drug that would have been suitable to use in a large gathering of persons such as at Eleusis, where most or all participants would have been previously inexperienced with psychedelic drugs.
Topic: n-hydoxyethylsergic acid amide and it's lsd equipotent n-butylhydroxylysergeamid (Read 741 times)
adducts_paper.pdf
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