i've only taken the citrate once but i've taken the hcl salt hundreds (thousands?) of times at all varying ranges in regard to dosing and i agree with shake's evaluation of the citrate salt 100%.  i'd recommend people try it, it's pretty unique in its own right and i'm happy i tried it, in fact i plan on trying it again at some point soon.  but i agree it lacks empathy and rushing, it's a pretty mild experience in comparison to the hcl salt.  still, it's a worthwhile drug and is worth the time of trying it out.  i think a mixture of citrate and hcl would be bomb but have yet to try it.  i've tried mde and mdma combo and love it (i don't like mde on its own too much).  i'd bet the citrate adds a mellower more dreamy aspect to the typically very clear-headed mdma hcl experience.

LOL shake, no.

If you are doing a scientific trial, then you need consistency and to measure out quantities, if you want to be able to draw valid, accurate conclusions. If doing a double-blind (or single blind, if thats all that is achievable practically speaking), then failing to weigh your drug, and for that matter, abusively using every night, no shit, its going to render any conclusion invalid.


ROFL jon, paedophilic....I'm glad I finished eating, else I would have hawked a pot-noodle loogie all over my screen at that one!

Crossing the BBB more effectively, that doesn't hold much water for me, its going to be in its ionized, dissociated form once it makes it into the bloodstream, in which case, it doesn't matter what the counterion is, as the two will no longer be bound together. The more lipophilic a substance is, the FASTER it gets absorbed actually, ionic species don't penetrate fat and cell walls anywhere near as effectively, and strongly polar compounds don't pass the BBB as easily either, barring those substances such as glucose, and aminoacids that undergo active transport, and small, polar molecules that are too small to be easily blocked.

If you want to demonstrate that, time the onset of a rectal dose of GBL, and compare with that of GHB. I have had GBL hit that way within five minutes, thirty seconds. Compared with quite a bit longer for GHB. I don't advise using either, mind you, due to the GHB-receptor mediated excitotoxic potential.

Out of curiosity, pretty confident it will be as the base, but anyone know if plasma protein-bound drugs are bound in the dissociated form or not? and for that matter, what the plasma protein binding percentage is for MDMA?

Citrate is the conjugate base of citric acid and would be a water-solubilizing group.  My medicinal chemistry book says that "Basic water-solubilizing groups have a tendency to change the mode of action, since bases often interfere with neurotransmitters and biological processes involving amines."  It says acidic water-solubilizing groups are not very likely to do so.