Im suprised that no one is discussing the conversion of cinnamaldehyde to P2P using the Huang Minlon elimination followed by standard peroxidation of propenylbenzene to P2P. I would love to hear reports on this.

There are so many means to an end I fail to understand why majority of people take the most complicated, time consuming, and expensive means of all by extracting 20 boxes of pills and then hunting for Iodine, and scraping the backs of sometimes over 10,000 books of matchs to yeild maybe an ounce of product.

Reducing (pseudo)ephedrine does give enantiomerically pure product.

I think the labor intensive methods caught on mainly because they didn't require any real talent for chemistry, and since the users were going to be up all night anyway, they'd might as well scrape some match books.

A lot of chemists seem to write off MA syntheses as not worth exploring since someone with no talent can in theory arrive at the same end product, but there are plenty of interesting pathways worth exploring and many of the processes should apply equally well to MDMA synthesis.. (MD)phenylacetic acid, (MD)benzaldehyde, etc..

I thought Hex was talking about a nitroethene, which I thought could of been of interest, if the prep was easy etc, and then this reduced. I have also thought of preparing 2-nitroethanol, and adding sodium bisulfate to remove the OH and create unsaturation, that then could be reduced. I need to think about this more, and be dam careful about playing around with lower alkane nitro compounds. I may well buy some silver and make the silver nitrite and do that prep. It is the challenge that is of interest. but yields help.

Reaction of Acetone and benzene, and the inclusion of Manganese(111)acetate as catalyst.

I actually hadn't seen this before, but this seems extremely straightforward.  I believe it could add properly to (MD)benzene too.

http://www.erowid.org/archive/rhodium/chemistry/manganous.acetate.html

Benzene isn't OTC (though you can find it online sometimes) but can be produced from sodium benzoate and likely a few other methods.

video demo:  hxxp://www.youtube.com/watch?v=sYyw_hrXrZ8


I know brominating (md)benzene tends to mostly add in the para position where you want it, which is why I believe this might add properly.  (I'll try to find some references.  I've never seen any directly pertaining to producing 1,2md-4-bromobenzene other than as an intermediary to other products, but it seems to work about the same way as producing bromobenzene.)

I have given some thought before to the enolate method.  Here are a couple versions of an org. chem. class lab procedure demonstrating aldol condensation using NaOH to form the enolate rather than stronger bases that require more preparation.

hxxp://www2.volstate.edu/chem/2020/Labs/Aldol_Condensation.html
hxxp://www.chm.davidson.edu/erstevens/381aldol.pdf

I do not know if polymers would try to form with P2P and bromobenzene although it seems fairly likely and has been my main concern with the enolate method.  Unfortunately, I don't currently have lab access to try it.

Reaction of Acetone and benzene, and the inclusion of Manganese(111)acetate as catalyst.
Yields arent great aprox 36%, but with cheap solvent and cheap(OTC) reagants fullstop, this appears to be worthy of another mention.

Figure how much manganese acetate is needed and the it becomes ugly.

I've seen nitroethane synth, how bout something like nitromethane

Off topic much? Perhaps you meant to post this in the nitroethane section?

Sorry about the delay. I feel like I gave birth to this threed just to get charged with child abandonment.
My minds been really wraped up in other reactions and personal shit lately.

However, you will not find much literature in forums on this other then a few threeds here and there unless you dig thru carefully because those who know ain't talking much and for good reason. Its an acid cataylised aldol condensation between BnO and MEK. This can be reversiblely hydrolysised to Hydroxyl Methyl Phenyl Butanone so anhydrous conditions are absolutly needed. (anhy)HCl has had the best first hand yeilds from what I have heard here and there but Concentrated H2SO4 can also be used. Also it can more then likely be performed under the influence of a strong Lewis acid + H2O2 combination.

The formed MePhBuO is oxidised to the intermediat Phenyl-propenyl-acetate which further reacts in the (aq)acidic enviroment hydrolysis to yeild Phenyl-2-Propanone. This is has been reported although not in forums that I am aware of to be highly exothermic so care must be taken to slowly care for the reaction speed.

My honestly belief is that of most others that have heard of this reaction chose not to make it a wide spread idea and thats that best case because all it takes is one lab to go down thru this process and all the sudden you get funny looks trying to buy the materials and after that there completely off the shelfs. Best bet is to understand the reactions, read up, and communicate everything first hand via PM. I do alot of restoration work on old furniture and would hate to see my favorite MEK paint strippers go the way of the doe-doe. Its already bad enough I can't bake my favorite cherry candys without looking suspicious I would hate to lose the other half of the hobby.

Saponification with NaOH is not needed as far as I know and on the previous page delic posted a reaction schematics of the reaction the hydrolysis is handled thru the acid. Look over at SciMad for some decent threeds on this topic also.

Now if you don't mind Sedits going to indulge in some malt EtOH and Benzodiazepines so for the rest of the night take his word with a grain of salt. HAPPY freedom day in 30 mins every one.