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Klot
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| Joined: 14 Feb 2005 |
| Posts: 93 |
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581.06 Points
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re: Tempidone
Mon Sep 12, 2005 1:13 pm |
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Fentanyl analog from tenpidone is NOT active as a analgesic  in dose 100 mg/kg
in dose 25 mg/kg causes fall-off of AD , that results in mors any rats
Article on russian here
http://schwarzkunstler.narod.ru/kunst/82001.djvu |
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longimanus
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| Joined: 08 Aug 2005 |
| Posts: 5 |
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283.24 Points
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re: Tempidone
Sat Sep 17, 2005 12:39 am |
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A-ahm!
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Соединения VII (R = C6 H5 CH2 ; R' = C2 H5 ; R'' = CH3 ) и VII (R = C6 H5 CH2 ; R' = R'' = C2 H5 ) бьiли исследовани...
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And only this, only two compounds. None of which resembles in any acceptable degree fentanyl
Rather different, ain`t they?
Well, it appears that we actually do not know the activity of the compound in question yet.
And don`t you think it is rather strange that despite the purpose of the investigation was to find the analgesic activity of these compounds the only two tested were possibly the least promising? |
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re: Tempidone
Sat Sep 17, 2005 1:47 am |
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You would think that somebody somewhere would have looked into it by now. Perhaps the findings were so terrible that they didnt even consider their findings publishable? But then again nobody could have looked at it yet. You just cant predict that type of thing.
Last edited by Stinging_Nettle on Wed Sep 28, 2005 2:16 am; edited 1 time in total |
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simply RED
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| Joined: 22 Aug 2005 |
| Posts: 6 |
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169.38 Points
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re: Tempidone
Tue Sep 27, 2005 9:50 pm |
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| Why tempidone has to be converted to its toluensulfonic salt? |
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