MDEA vs. MDMA workup

[methlab]

Hi! Could not dissolve MDEA crystalls in IPA until a few drops of water added. Are there more differences on the workup between MDEA and MDMA? I thought they are 'nearly' the same...

[foxy2]

Thats hard to believe, intuitively I would expect it to bee more soluable than MDMA in IPA.

Perhaps you didn't use enough IPA? did you heat it also? It may just bee slow to dissolve.

[Rhodium]

Thats hard to believe, intuitively I would expect it to bee more soluable than MDMA in IPA.

Solubility intuition only works for inorganic compunds and other things not forming hydrogen bonds and other mischief.

A case in point is the insolubility of 2C-B·HCl in water, while DOB·HCl, 2C-C·HCl and 2C-I·HCl all have good aqueous solubility.