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Structurally simple cocaine analogs -Beagle

Started by dormouse, April 23, 2000, 04:32:00 AM

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Skindeep_Assrash

Here Yee, Here Yee!  Cocaine's NOT worth the study time! Actually, I'm typing out of my assrash again, I haven't SEEN  any decent cocaine around for sometime, it always seemed so TERRIBLE of a high. But I can remember getting some nice pink turtle shell back shale back in the late '80's. Too bad I wasn't into fixing dope back then! That would've been RAD! ;D

-Assrash Ouch!

Gen_Washington

Could someone post the simple, in plain english, "I know someone with the money and equipment but not the jargon literacy" technique for making of "1M 4-
chlorophenylmagnesium bromine" ?  Thanks ahead, many. (re order that, or just forget it, or)

Bwiti

4-methoxy-bromobenzene is easier to obtain. Is it worth extracting arecoline from betel nuts?

  The christian god hates your soul. Care for a little necrophilia?

Rhodium

4-methoxy-bromobenzene would also be easier to form the grignard reagent from (4-methoxy-phenylmagnesiumbromide has a molecular weight of 211, so a 1M solution of this would contain 211g/1000ml solution. In regards how to prepare it from 4-methoxy-bromobenzene, see step 2 in

https://www.thevespiary.org/rhodium/Rhodium/chemistry/4-meo-pcp.html

).

As for extracting arecoline from betel nuts, they have an alkaloid content between 0.15-0.67%, of which Arecoline is the major alkaloid. Some of the minor ones are arecaidine, guacine, guvacoline and arecolidine. I don't know how effectively arecoline could be separated from the other alkaloids, but commercial arecoline is pretty cheap anyway.

Rhodium

What specific compound are you trying to make? And from what starting materials?

Rhodium

I don't think you should be doing this synthesis if you are not even sure what it is you are trying to make.