P2P-derivate related

[Vitus_Verdegast]

Both methyl-phenylacetat and benzyl cyanide are on the list.

http://de.vwr.com/app/Header?tmpl=/dienstleistungen/bestellverwaltung/eve_freiw_selbst.htm

The idea was to generate P2P from easiely available chemicals

Well, what about the benzaldehyde/MEK aldol condensation, followed by a Baeyer-Villiger (twodogs' procedure)? Sure the yield is a bit low, but still acceptable and all your precursors are cheap as dirt and easily procured.

Post 451381

(bio: "Benzaldehyde + MEK acid catalyzed aldol", Methods Discourse)

[politoxicomania]

Ok
Phenalaceticacid and benzylcyanid are voluntarily watched in germany, but if u look into calalogues of chemicals like acros, aldrich or what else u will find that some precursors are  "merck index". This is a sign for supplieres! Phenalaceticacidmethalester isnt on the merck index. It should be available much easier as Benzylcyanid.

[7is]

Why would they be watched just because they are mentioned in the merck index?

[Vitus_Verdegast]

There's "Merck Index" all over the Acros catalog, on every page practically, just like you have references to Fieser and Beilstein too. This has absolutely nothing to do with the watched status of a chemical.

Will you try to make me believe that aluminium sulfate, sodium carbonate, sodium chloride and glucose are watched then? They all have "Merck Index" next to them.

[Nicodem]

Maybe he thinks that the law enforcement officers dont't read something so huge like the Beilstein or CA and limit their chemicals knowledge to the Merk index. Just think of how huge the books about law are. They sure don't have a lot more space left on their shelves for anything but a short Merk index. That would sure make me laugh.

[hypo]

in some countries "normal" people are prohibited by law
from buying stuff that is rated as toxic. so even if your
chem-supplier doesn't give a shit about this self-crontrol
crap, he cannot sell you benzylcyanide because he needs
to prove that the guy whom it is sold to has a permit.

so yes, phenylaceticacid methyl ester might be no problem
to some bees who can't get benzyl cyanide. c'est la vie.

[politoxicomania]

Thanks hypo.....

[Nicodem]

OK, you can't buy chemicals rated toxic. That is sad because almost any imaginable reaction requires at least one reagent rated so. But how is this related with the catalogue number having a reference to the Merck index?

[hypo]

forget it already.
but the original point of cyanide vs. ester stands.

[Rhodium]

The second article in

Post 484608

(Rhodium: "Phenylacetic Acid -> P2P [ ThO2 Tube Furnace ]", Methods Discourse) discusses the use of esters in the tube furnace to produce P2P.