Prometheuz
(Newbee)
05-23-03 06:02
No 434954
       Sensibility of mercapto-groups to reduction  Bookmark   

After studying this excellent post Post 434950 (Chimimanie: "On 2C-T-x precursors", Novel Discourse), I wondered if the mercapto-group (or whatever it's called.... My nomenclature-skills are a bit rusty) can stand reduction with LAH?
I recon normal condensation with nitromethane would behave just fine with the compound (Z)?
My knowledge about sulphur-containing compounds is rather limited...
To fathom Hell or soar angelic
Just take a pinch of psychedelic 		 
 
 
 
    Chimimanie
(Hive Bee)
05-23-03 07:30
No 434967
       LAH  Bookmark   

Hi! smile thank you for your comments

Yes the 4-alkylthio groups are stable to LAH, its the way good doctor Shulgin use to synthetise the various 2-CT. (benzaldehyde ->  nitrostyrene --LAH--> amine)

see http://www.erowid.org/library/books_online/pihkal/pihkal043.shtml

For others question, please use the appropriate thread Post 434950 (Chimimanie: "On 2C-T-x precursors", Novel Discourse)