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java (Hive Addict) 09-28-04 21:24 No 533715 |
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Procedure for the Synthesis of Formyl Amides | ||||||
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A New, Simple Procedure for the Synthesis of Formyl Amides Lidia De Luca, Giampaolo Giacomelli,* Andrea Porcheddu, Margherita Salaris Abstract: A simple and mild method for the N-formylation of amines and a-amino esters is described via reaction with 2-chloro- 4,6-dimethoxy[1,3,5]triazine and formic acid. The reaction can be accelerated under microwave irradiation and yields the N-formyl species in high yields and without racemization in the case of optically active a-amino esters. SYNLETT 2004, No. x, pp 000A–000Cx.x.204 ![]() [image] Note:I think this can be used for the Monomethylation of amphetamines. It is better to die on your feet than to live on your knees...Emiliano Zapata |
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