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java (Hive Bee) 02-01-03 08:01 No 403276 |
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Synth of Ephedrine from protected Cyanohydrins (Rated as: excellent) |
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Stereoselectrive Syntheses of Ephedrine and Related 2-Aminoalcohols of High Optical Purity from Protected Cyanohydrins Jackson et al Tetrahedron Letters, 31, 10, 1447-1450 (1990) (https://www.rhodium.ws/pdf/ephedrine.gr Abstract: Ephedrine and related optically active b-aminoalcohols can be prepared by zinc borohydride reduction of aryl O-protected magnesium imines and aryl a-hydroxyimimes which in turn are readily available from optically active cyanohydrins. Saludos, from Latin america |
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