(Stranger)
11-07-02 20:59
No 377558
Can someone explain what happens in the reaction, and what are the best chemicals to clean and extract the freebase after the amalgum is finished.
(Chief Bee)
11-07-02 21:12
No 377561
https://www.rhodium.ws/chemistry/alhg.os
(Hive Bee)
11-07-02 21:24
No 377567
https://www.rhodium.ws/chemistry/alhg.os
+ a whole lot more in the search engine
I'm kind of 'on the fence' as to whether or not this should be in the newbee forum, but today is a great day.....
The simplest explanation of what is going on, and I assume you are talking about the nitro Al/Hg, is that the nitromethane is reduced to a primary amine (methylamine) by the amalgamated aluminum which condenses with the ketone to form an imine. This imine is further reduced to the secondary amine, also by the Al/Hg. Give you three guesses what the secondary amine is
The best (most commonly preferred) solvents to use are toluene or xylene, and an NaOH wash, a brine (saturated salt solution) wash, and a water wash are customary. Some people like to dry the solvent, prior to making the hydrochloride salt, with baked epsoms; but if your yeilds are good you probably won't need to bother.
EDIT: However, my timing seems to be horrible.
Pr(+)tium