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Loratadine |
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Loratadine
is a white to off-white powder not soluble in water, but very soluble in acetone, alcohol, and
chloroform. It has a molecular weight of 382.89, and empirical formula of C22H23ClN2O2;
its chemical name is
ethyl4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylate. Claritin
tablets contain 10 mg micronized loratadine, an antihistamine, to be
administered orally. They also contain the following inactive ingredients:
Corn starch, lactose, and magnesium
stearate. Claritin syrup contains 1 mg/ml micronized
loratadine, an antihistamine, to be administered orally. It also contains
the following inactive ingredients: Citric acid, artificial flavor, glycerin,
propylene glycol, sodium
benzoate, sugar, and water. The pH
is between 2.5 and 3.1. Claritin
Reditabs (rapidly-disintegrating tablets) contain 10 mg micronized
loratadine, an antihistamine, to be administered orally. It disintegrates in
the mouth within seconds after
placement on the tongue, allowing its contents to be subsequently swallowed
with or without water. Claritin Reditabs also contain the following
inactive ingredients: Citric acid, gelatin, mannitol, and mint flavor. |
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