Fusaric Acid

[MrSamosa]

This is an interesting chemical, as it is found in many plants as a poison. However, it is not an insanely complex structure. It is, in fact rather simple... I cannot draw a picture for you now, but the name should give you an idea: "Butyl Pyridinecarboxylic Acid." Basically, a COOH attatched to the 2 Carbon on the Pyridine ring, and a Butyl group attatched to the 5 Carbon.

It is acutely toxic, but I do not know its mode of action unfortunately. Its Oral LD50 in rats is abou 230 mg/kg. Nothing spectacular, but I do think it is worth some consideration.

Now, the questions... What precursors could be used in this? I found a relevant synthesis on a website, but unfortunately it is for registered users only! <a href="http://web.mit.edu/chemistry/rld/totalsyn/fusaricacid.html" target="_blank">http://web.mit.edu/chemistry/rld/totalsyn/fusaricacid.html</a> there is the link... does anyone have an account?

[nbk2000]

18 grams as an LD50 for a 70kg human is terrible! Better to make TEPP using the pyridine, which has a few milligrams LD50.

[Mr Cool]

Or maybe ricinine,
<img src="http://www.latoxan.com/IMG/6012.gif" alt=" - " />
LD₅₀ of around 20mg. It would be quite a bit more complicated to make though.

[Boob Raider]

It is obtained in the acetone fraction along with cellular lipids of the castor bean pulp. The acetone fraction doesn't contain any ricin so its toxcicity is due to ricinine. I posted some ricin info in the Ricin/ethanol/acetone thread. But an LD50 of 18 grams is pathetic. There are tonns of other things more toxic than that.