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HydroCodone -> OxyCodone?

Started by EvilMadChemist, August 12, 2004, 11:23:00 PM

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EvilMadChemist

ive searched the search engine , cant find anything,  im wondering how hard would it be to convert HydroCodone to OxyCodone?

Rhodium

https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000525100-oxycodone.jpg" target="_blank" title="View this image">
Oxycodone

Hydrocodone has a structure very similar to the above - it just lacks the OH group in the 14-position.
However, I am not aware of any easy method which would be able to reduce that -OH to -H without at the same time messing up the ketone in the 3-position or any other unwanted mischief.


EvilMadChemist

Thanks Rhodium thats what i thought, i noticed they where the same structure beside the OH and H, but i was hoping there might been easy way for a newbee.