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3-Trifluoromethylphenylpiperazine route?

Started by catharsis, August 15, 2000, 03:14:00 AM

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catharsis

I'm sure you could use isosafrole, or pieronal..but i'm no chemist and id like to know inof on how to achive this chemical.. It's said on rhodiums pharmaclology page, that this chem mixed with benzylpiperazine mimcs MDMA, or is prefered by lab animals over MDMA.. Any starting points would be appreiciated as i'm not a chemist. thanks.


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purge the info.

Skink


Osmium

Piperazines from safrole or isosafrole??????

catharsis

doesnt seem beyond the reach of isosafrole.. at least not from what ive read..i dont know if what i read was credible or not..but i think rhodium posts credible things.


purge the info.

Rhodium

Start with trifluoromethylbenzene and nitrate it in the 3-position. Reduce the nitro group to an amine. The 3-trifluoromethylaniline is then condensed with bis(chloroethyl)amine hydrochloride to give 3-trifluoromethylphenylpiperazine. Or you could buy it from an online supplier of research chemicals.


http://rhodium.lycaeum.org