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Alkylation using bromides

Started by Bandil, May 05, 2002, 01:36:00 PM

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Bandil

Hi!

Swim has way to much potassiombromide for him to use, so he tought he would use it to make som nice n,n-alkylated tryptamines(the legal ones). If swim was to prepare propylbromide, like described on rhodiums page, he though that would be nice.

How does the reaction with (iso)propylbromide with tryptamine compare to the reaction of (iso)propyliodide with tryptamine? Swim supposes its slower, but how much, and how does the yeilds compare?

All in all, is it worth doing with the bromide, or should swim get off his lazy ass and get some iodide?

Thanks!

Regards Peter