An Efficient Synthesis of Indole

[pHarmacist]

Yoshihiko Ito, Kazuhiro Kobayashi, Takeo Saegusa;

Author's Voice: [...]Herein, we wish to report a new and versatile synthesis of indole derivatives based on selective ortholithiation of the alkyl group in o-alkylphenylisocyanides and subsequent intramolecular ring closure.[...]

J. Am. Chem. Soc.; 1977; 99(10); 3532-3534.
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Fulltext:

http://pharmacist8.tripod.com/o-isocyanotoluenes.pdf

[pHarmacist]

Post 446390

(pHarmacist: "ortho-isocyanotoluenes in indole synthesis", Tryptamine Chemistry)