3-methylfentanyl

[Cyrax]

What is the chemical structure of 3-methylfentanyl?  Can someone draw me a structure formule?

Thx

[altair]

EtCo   Ph
       \ /
        N
    Me  |  
     \/   \
      |   |
      \   /
        N
        |
        \
      |
        Ph

something like this perhaps?
btw
this was then what now

[slappy]

That is correct. It should also be noted that only (-)-cis-3-Methylfentanyl holds the extreme potency. Fentanyl is achiral, when you introduce that methyl group, you end up with 4 enantiomers.

[Cyrax]

Isn't it amazing that 3-methylfentanyl is 30 times more potent than fentanyl ?

What about an enamine alkylation a la Stork to make the
3-methyl-4-piperidone?

Does anyone has refs. about the synthesis of 4-piperidone?

[slappy]

Let me put it this way...

Attempted synthesis of 3-Methylfentanyl without a glovebox == Death