Pepper to make MDMA?

[malvaxman]

Has anyone here yet used black pepper to make MDMA on at least a medium scale? With which result?
Is sassafras-oil possible to buy OTC in South-East Asia,
where should i look then?

Thank you for your answers.

[Rhodium]

I don't know of anyone trying out black pepper as a MDMA precursor in reality yet, but the theoretical details can be found at my page.

Sassafras oil is available from several asian vendors, name the country and I'll give you a few hints in a PM.

[PrimoPyro]

do u mean the piperonal to mdma route? pepper is cheapo cheapo... good luck.
Of COURSE we don't know what we're doing! That's why it's called research!  (boom...)    

[Rhodium]

Piperine (found in black pepper) can be oxidized to piperonal (3,4-methylenedioxybenzaldehyde), which can be converted to MDMA.

[obituary]

obit knows a bee who has reported success all the way throught the amination.  small scale though- ~2g final product.  but it does work!

[tomjuan]

Doesn't black pepper contain a small amount of safrole as well? Like 0.6 - 1.0%? The synths I have seen always extract the piperine and convert it to piperonal. The one I am looking at right now got 1 gram of piperonal from 100g of black pepper, and it took a lot of time and effort. But if pepper really has a 0.6%-1.0% safrole content, they could have gotten almost a gram of safrole from the same 100g of black pepper, presumably with less time and trouble.

Any thoughts on this?

[Rhodium]

Is there a detailed writeup of this pepper -> piperonal available, other than the one by "The Cook" on my page?

[tomjuan]

The one by "the cook" is the only one I have seen any details about. I have seen a usenet thread that had that same write-up as well as some responses about succeful and failed attempts. Apparently, over oxidation was the main mistake made in the attempts. I'll see if I have that whole thread saved somewhere so I can post it for everyone.

[obituary]

report that obit received yeilded around 3-5g piperonal/ 100g pepper- obit thinks that isn't too bad.  not anything to get excited about, but what the heck.

[cheesie]

my results were very similar! around 4grams of piperonal in relation to 100grams of pepper.It is a good source especially after several rxns a nite!
Talk to me munky.
Munky.
Talk to me!

[obituary]

Hey Cheese- obit was referring to you. duh.

[cheesie]

ooooppps! how embarrising!hehe oh well secrets out now, i'll have to do a write up for the bees (god i hate write ups i always fuck up on them then get flamed to shite)
On my next run down i will write up all i dreamed then post it in the newbee section okie cokie!obit you will get first crack at the write up so u can look over it!oh and u 2 rhodium or who ever is the moderator on this forum!
Talk to me munky.
Munky.
Talk to me!

[tomjuan]

Okay, so I guess that clears it up - but I have a related question (assuming the department of agriculture is correct about the safrole content). If I extract the pirerine with ethanol, is there safrole in my extract as well? Or would the safrole need to be gotten at by a diffrent method?

[cheesie]

pirerine?
Talk to me munky.
Munky.
Talk to me!

[obituary]

is safrole soluble in ethanol?- then that's your answer.

[tomjuan]

yes, piperine - it is the alkaloid in black pepper that piperonal is allegedly derived from. The methods I have seen take the route:

Pepper -> Piperine -> Piperic Acid -> Piperonal

But I am every bit as a interested in the safrole. No one has had experience extracting safrole from black pepper?

[tomjuan]

Allegedly it IS soluble in ethanol. However, that method of extraction doesn't seemed to be used when extracting safrole from sassafras root bark - all the literature seems to recommend steam distillation.

[cheesie]

sorry i though you called it pirerine earlier on! never done the pepper synth for saffrole so i can't hlp on that score.
Talk to me munky.
Munky.
Talk to me!

[tomjuan]

oh oops - you are right - I did. Sorry for the typo.

[cheesie]

thats cool like i said watch out for my write up in the newbee section or do u all want it in here?
Talk to me munky.
Munky.
Talk to me!

[obituary]

doesn't really matter were you place it, but it would be best if you placed it in it's own, new thread.

[tomjuan]

Well, I am a newbie, so don't listen to me - but it seems we don't have detailed method anywhere that gives nearly the yield you are getting. So I think it might be appropriate to post it in a new thread in either this forum or the "Novel Discourse" forum. Wherever you end up posting it, it'll be greatly appreciated. Thanks in advance

[cheesie]

and god spoke and thus was done! i will, like i said obit u will get first crack for your undivided attention to detail, then a moderator then after clearance i will post it okay?
is this okay for everyone concerned?

Talk to me munky.
Munky.
Talk to me!

[obituary]

cheesie, no prob.  send it whenever you finish the next round and obit'll get the ball rolling on the editing.  hey cheesie, do obit one favor though- make it a big batch. so you can have a good weekend!

[cheesie]

i'll try with the funds available, currently on several dreams at the moment which are draining funds, BUT i will do a fairly big one just for you!
just give me some time okie cokie.
now wheres that meth gone.............*mwah*  
Talk to me munky.
Munky.
Talk to me!

[jim]

I am having trouble finding any sort of reference for piperic acid to piperonyl.

It would be nice to have a more selective oxidation from piperic acid. 

I can't find this
Fittig and Mielch, Ann., 152 (1869) 25)

Could some one else get these:
J. Am. Chem. Soc. 94, 4024 (1972);
J. Org. Chem. 43, 1532 (1978)

How about these other routes to the aldehyde:
chromyl trichloroacetate: Liebigs Ann. Chem. 659, 20 (1962)
t-butyl iodoxybenzene: Tetr. Lett. 26, 4955 (1985)
KMnO4 in THF-H2O: J. Org. Chem. 51, 3213 (1986)
NaIO4-OsO4: J. Org. Chem. 21, 478 (1956)
Synthesis 1984, p 431-3
 J. Chem Research - Synopses 1986, p 458-9
Dimethyl polyethylene glycol - see J. Org. Chem. 43, p 1532, (1978).

[obituary]

obit'll try and find some of those and get back with you

[cheesie]

hi munky!if u get them can u pm them to me as well?
*mwah* ur a star!
Talk to me munky.
Munky.
Talk to me!

[Skindeep_Assrash]

Hell, if i lived in SE Asia, I'd be finding an MDP-2-P source, fuck the safrole! um, PM ME!
Assrash Ouch!