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BROMO SAFROLE

Started by Vibrating_Lights, June 10, 2003, 11:01:00 AM

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Vibrating_Lights

Is ity possible to hydrolize Bromosafrole to MdP2POL With
NaOH Heat and H2O?
VL_


hypo

to increase reaction speed, you might either work with
an organic solvent/PTC system or in alcoholic solution.
hydrolysis also works in acidic medium (ie. dil. H2SO4).
you'll always get some elimination side-reaction.

now the $100.000-question is: why would you want to do
that? (halo-safrole => MDP2P?)

Vibrating_Lights

It is national bromine month.


hypo

thanks for your cooperation  :P

Rhodium

That reaction sounds like you are going to get isosafrole as your major product (elimination instead of substitution).

https://www.thevespiary.org/rhodium/Rhodium/chemistry/halide.carbonyl.html

is much better, and if you really want MDP2Pol, reduce the product from this reaction.