The Vespiary

The Hive => Methods Discourse => Topic started by: mtnfrogger198 on March 24, 2003, 10:39:00 PM

Title: Leftover Safrole...
Post by: mtnfrogger198 on March 24, 2003, 10:39:00 PM

If there is unconverted safrole in swim's freshly distilled isosafrole, what happens to it during the epoxide formation (Performic Acid Reaction)? Will it hurt anything in later reactions?

Title: A little clairification.
Post by: mtnfrogger198 on March 24, 2003, 11:15:00 PM

Swim asked this because swim found reference to reversing the isomerization process using an acid.

The confusion arizes because the isosafrole is being added to an acidic solution (extra formic acid in the peracid mixture).

This implies that Safrole could be used in place of isosafrole, saving a lot of time, effort, and precursors.

Title: errors
Post by: Rhodium on March 24, 2003, 11:21:00 PM

You cannot reverse the isomerization and turn the isosafrole back into safrole using acid. Where did you read that?

Peracid oxidation of safrole will not yield anything immediately useful either.

Title: the source of errors...
Post by: mtnfrogger198 on March 24, 2003, 11:46:00 PM

I found this reference on the web (I don't remember the exact source... but it wasn't on your ws).

Thanks again Rhodium!  ;)