Author Topic: 5-meo-dmt  (Read 2580 times)

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taranis

  • Guest
5-meo-dmt
« on: August 21, 2001, 09:12:00 AM »
I have a novel idea on a possable synth for this interesting
tryptamine. i would like any bee's advice.
starting from melatonin with lah reduction to yeild
5-meo-et (ethyl tryptamine) then treated with HNO3 at 0c
and further treated with warm dH2O yeilding 5-meo-hydroxy-t
wich could be put through any of varyos forms of rductive
amination
any input would bee much apreceated.
thnx

taranis

  • Guest
Re: 5-meo-dmt
« Reply #1 on: August 21, 2001, 09:49:00 AM »
oops i just found some info on this. but maby it is worth further discution

Lilienthal

  • Guest
Re: 5-meo-dmt
« Reply #2 on: August 21, 2001, 05:44:00 PM »
Coool, animated tryptamines...  :)

Bwiti

  • Guest
Re: 5-meo-dmt
« Reply #3 on: August 24, 2001, 06:15:00 PM »
I would kiss the ground someone walks on if they can find a use for melatonin, because it's cheap. Maybe a reduction with NaBH4, catalyzed by nickel boride would create something worth ingesting? Either way, this is an exciting topic! :P

  I'm going to help all of you cleanse this diseased planet.

Rhodium

  • Guest

Bwiti

  • Guest
Re: 5-meo-dmt
« Reply #5 on: August 25, 2001, 01:24:00 PM »
Yep, I've seen the mexamine synth, but I don't know if it's active?  :P

  I'm going to help all of you cleanse this diseased planet.

jim

  • Guest
Re: 5-meo-dmt
« Reply #6 on: August 25, 2001, 03:26:00 PM »
You could try alkylating the mexamine into something more interesting.

Try using MeX and poly(ethylene gylcol) in water, or alcohol.  Or even isopropyl chloride...

taranis

  • Guest
Re: 5-meo-dmt
« Reply #7 on: August 26, 2001, 12:09:00 PM »
mexamine is 5-meo-nmt. acording to tihkal it is  as far
as we know not active.

Zen

  • Guest
Re: 5-meo-dmt
« Reply #8 on: January 09, 2002, 11:55:00 PM »


"I would kiss the ground someone walks on if they can find a use for melatonin.." -Bwiti



Over here next to me, it's a spot where Shulgin stepped.

Melatonin > 5-Meo-DIPT

-Zen

Ref: Tihkal

"To a solution of 3.0 g 5-methoxytryptamine (see under melatonin for its preparation) in 20 mL sulfolane (tetramethylenesulfone) there was added 8.2 g diisopropylethyl amine and 10.7 g 2-iodopropane, and the two-phase mixture was heated on the steam bath with frequent shaking. After 3 h, the mixture was brought back to room temperature and stirred vigorously for an additional 16 h. After the removal of all volatiles under vacuum, the residue (30 g) was diluted with 100 mL H2O, which gave a clear solution. The addition of 10 mL 5% aqueous NaOH produced a cloudy suspension that was extracted with 3x40 mL hexane. These pooled extracts were stripped of solvent to yield 1.0 g of an almost colorless oil that was distilled at the KugelRohr. A small cut at 100 °C (at 0.01 mm / Hg) proved to be largely residual sulfolane (about 0.01 g) and the bulk of the product distilled at 140-150 °C to give a viscous white oil, 0.80 g. This was dissolved in 3.5 mL IPA and neutralized with 15 drops of concentrated HCl. The addition of five drops of anhydrous Et2O instigated crystallization, and the product was removed by filtration, washed with 4:1 IPA / Et2O mixture, and air-dried. There was thus obtained 0.85 g of a fine white crystalline product, 5-methoxy-N,N-diisopropyltryptamine hydrochloride (5-MeO-DIPT), with a mp 181-182 °C (17%). IR (in cm-1): 731, 809, 826, 931, 1035, 1064, with an NH at 3165. MS (in m/z): C7H16N+ 114 (100%); C4H10N+ 72 (31%); methoxyindolemethylene+ 160 (12%); parent ion 274 (<1%). There was no detectable 5-MeO-NIPT by GC (<1%)."

http://www.erowid.org/library/books_online/tihkal/tihkal37.shtml


Lem2

  • Guest
Re: 5-meo-dmt
« Reply #9 on: January 29, 2002, 05:18:00 AM »
jim, "Try using MeX and poly(ethylene gylcol) in water, or alcohol." could you please elaborate? Does poly-ethylene glycol stop the formation of the quaternary salt?

He who makes a beast of himself gets rid of the pain of being a man.

cheeseboy

  • Guest
Re: 5-meo-dmt
« Reply #10 on: February 05, 2002, 10:42:00 AM »
What kind of high does mexamine produce?

May The Source Bee With You....Always.

  - OB1KNoBee

Rhodium

  • Guest
Re: 5-meo-dmt
« Reply #11 on: February 05, 2002, 04:26:00 PM »
None. It must be dialkylated on the nitrogen first. Mexamine is 5-MeO-Tryptamine.