What you probably mean is the solubility of ergolene derivatives?
Peptide alkaloids from Claviceps purpurea, like ergotamine, are typically extracted with chloroform, and are very soluble in solvents like this.
"Water soluble" lysergic acid amides, like those from morning glories and Claviceps paspali are also first extracted with chloroform or similar, but using much larger volumes than for the peptide alkaloids.
So it depends on the nature of the alkaloids which way to extract.
After extraction, extract the chloroform with for example aqueous tartaric or maleic acid, or even dilute hydrochloric acid.
There is a good example for extracting Claviceps paspali culture in Patent US3038840 (http://l2.espacenet.com/dips/viewer?PN=US3038840&CY=gb&LG=en&DB=EPD)
("Process for the production of alkaloid derivatives of lysergic acid"), beginning in column 4, line 10.