Compilation for GBL and GHBPreparation of salts of GHB/GBLhttps://www.thevespiary.org/rhodium/Rhodium/chemistry/ghb-r-us.txt
GABA to GHBPost 394630 (missing)
(Chromic: "Success making GBL!", Chemistry Discourse)Post 364288
(Rhodium: "GABA -> GBL + GHB", Chemistry Discourse)Comment on distillation of GBL from this particular reaction mixture:Post 375796
(Rhodium: "If you acidify the solution slightly (pH 4-6), ...", Chemistry Discourse)Physical Properties of GABA:Post 375570 (missing)
(Chromic: "Question your GABA", Chemistry Discourse)Note on the Formation of Nitrosamines in this Rxn:Post 378237 (missing)
(fierceness: "nitrosamines", Chemistry Discourse)Post 412468 (missing)
(hCiLdOdUeDn: "Nitrosamine decontamination", Chemistry Discourse)GBL, 1,4-butanediol, and THFPost 414046 (missing)
(roger2003: "German Dissertation about industrial scale...", Chemistry Discourse) (in german)
https://www.thevespiary.org/rhodium/Rhodium/chemistry/gbl.synthesis.microgram.html
GBL from 1,3-PropanediolPost 489813
(Rhodium: "GBL synthesis starting from 1,3-Propanediol", Methods Discourse)GBL/GHB from 1,4-butanediolOxid. with NaOCl and RuCl2Post 444525 (missing)
(Vitus_Verdegast: "I'm in a typ-o-maniacal mood today ;-)", Methods Discourse)Oxidation with Permanganate:Post 243620
(foxy2: "Re: Easy Oxidation of THF to GBL", Novel Discourse)Oxid. to GBL with various reagentsPost 441399 (missing)
(Rhodium: "1,4-BD -> GBL (76%) w/Trichloroisocyanuric Acid", Methods Discourse)Post 441437
(Rhodium: "Chem. Abs. 130:24638.", Methods Discourse)Post 441438
(Rhodium: "Chem. Abs. 130:313445", Methods Discourse)Post 442866
(Rhodium: "1,4-BD -> GBL (92%) using NaBrO2/Alumina", Methods Discourse) (typed version next)
Post 443378
(Vitus_Verdegast: "article typed up", Methods Discourse)Reaction with N-Haloamides:Post 246415
(Rhodium: "Re: Easy Oxidation of THF to GBL", Novel Discourse)Dehydrogenation of the Diol:https://www.thevespiary.org/rhodium/Rhodium/chemistry/bd2gbl.html
Post 441834
(Rhodium: "1,4-Butanediol to gamma-Butyrolactone in French", Methods Discourse) (in french, same as next link)
Post 441898 (missing)
(GC_MS: "1,4-Butanediol to gamma-Butyrolactone in English", Methods Discourse)(in english)
Post 449422
(Rhodium: "Maybe activation by pre-reduction is needed?", Chemistry Discourse) (dehydrogenation catalyst information/idea)
Oxid. with Hypohalite:https://www.thevespiary.org/rhodium/Rhodium/pdf/bd2gbl.pdf
Other References for Use of Diol:https://www.thevespiary.org/rhodium/Rhodium/chemistry/bdo2gbl.html
Synthesis of 1,4-butanediolPatent US6486367
Patent US6100410
Post 471608
(Rhodium: "Maleic Anhydride + BDO -Zn/Cu-> 2 GBL", Novel Discourse)GBL/GHB from THFOxidation with Bromate:Post 214379 (missing)
(foxy2: "Re: New(?) angle on THF > GBL", Chemistry Discourse) https://www.thevespiary.org/rhodium/Rhodium/pdf/thf2gbl.pdf
(includes mechanism)
Post 242315
(Rhodium: "Easy Oxidation of THF to GBL", Novel Discourse)Post 243615
(foxy2: "a multi-purpose oxidant", Novel Discourse)Experience with ox. bromate/H2O2Post 474583
(Beeswax: "Modification: Bromate oxidation THF -> GBL", Methods Discourse)Oxid. with Trichloroisocyanuric acidPost 444004 (missing)
(Aurelius: "Trichloroisocyanuric acid, ethers to esters", Methods Discourse)Post 446457 (missing)
(Aurelius: "Ether Oxid. Tet. 27, 2671-2674, (1971) THF-GBL", Methods Discourse)Post 340852
(Captain_Mission: "GBL from THF using trichloroisocyanuric acid", Novel Discourse)Oxidation with Permanganate:Post 243620
(foxy2: "Re: Easy Oxidation of THF to GBL", Novel Discourse)https://www.thevespiary.org/rhodium/Rhodium/pdf/solventfree.kmno4.oxidation.pdf
Experience with a permanganate oxidation:Post 304838 (missing)
(Antimony: "Cheap Easy GHB -No Bromate", Newbee Forum)Oxid. wth Fe+2:/I]
Post 243627
(foxy2: "Ultimate Easy and Cheap THF to GBL", Novel Discourse)
Oxid. wth Peroxyphosphoic acid:/I]
Post 243635
(foxy2: "Re: Easy Oxidation of THF to GBL", Novel Discourse)
Oxid. wth Br2:Patent US3074964
Catalytic Oxid. with O2:Post 364181
(moo: "Catalytic oxidations of THF with 1 atm O2", Methods Discourse)Oxid. with CoCl2: Not suggested b/c of nature of oxidantPost 364181
(moo: "Catalytic oxidations of THF with 1 atm O2", Methods Discourse)Oxid. with Calium HypochloritePost 3958 (missing)
(Fuchem: "Oxidation of THF to GBL from Tetrahedron Letters", Chemistry Discourse)Electro-synthesis of GBL from THF:Post 243610
(foxy2: "Re: Easy Oxidation of THF to GBL", Novel Discourse)Very similar to the above (from patent SU523093):Post 381459
(moo: "THF -> GBL patents etc.", Methods Discourse)Patent US3074964
Other References for THF to GBL/GHB:https://www.thevespiary.org/rhodium/Rhodium/chemistry/thf2gbl.html
GHB/GBL from Succinic and Maleic acids and anhydridesBunch of US patents related:Post 225945
(encopo: "GHB via GBL/THF via MAN via n-butane", Serious Chemistry)Post 466341
(Rhodium: "Reduction of Succinic Anhydride to GBL", Methods Discourse)Post 471608
(Rhodium: "Maleic Anhydride + BDO -Zn/Cu-> 2 GBL", Novel Discourse)GHB/GBL from CyclobutanoneJust an ideaPost 67503 (missing)
(Teonanacatl: "Cyclobutanone --> GHB", Novel Discourse)GBL from GHBPost 511270
(Rhodium: "Convenient Synthesis of ?-Butyrolactone", Chemistry Discourse)Physical Properties and Detection of GHB and GBLPhysical Properties and Detection of GHBhttps://www.thevespiary.org/rhodium/Rhodium/pdf/ghb-gbl.colortest.pdf
https://www.thevespiary.org/rhodium/Rhodium/chemistry/ghb.forensic.html
Chromic’s Use of the above method for GHB determination (both links):Post 377846 (missing)
(Chromic: "What the fuck???", Chemistry Discourse)Post 377847 (missing)
(Chromic: "Dilution was the key", Chemistry Discourse)Physical Properties and Detection of GBLhttps://www.thevespiary.org/rhodium/Rhodium/pdf/ghb-gbl.colortest.pdf
https://www.thevespiary.org/rhodium/Rhodium/chemistry/ghb.forensic.html
Post 449374
(Rhodium: "Cu Chromite dehydrogenation of 1,4-BD and GBL", Chemistry Discourse)Post 449918
(LaBTop: "GBL MSDS", Newbee Forum)Purification of GBL/GHBPost 214381 (missing)
(foxy2: "PURIFICATION OF GAMMA-BUTYROLACTONE", Chemistry Discourse)Misc. Stuff I haven’t organized yet:Enzyme stuffPost 317357
(Chromic: "Some GHB/BDO answers (sorry for the delay...)", Chemistry Discourse)https://www.thevespiary.org/rhodium/Rhodium/chemistry/ghb.html
Has information on analoguesPost 446659 (missing)
(OcoteaCymbarum: "Uses for gbl", Chemistry Discourse)Post 446714
(OcoteaCymbarum: "Industrial production of gbl", Methods Discourse)Analogues:https://www.thevespiary.org/rhodium/Rhodium/chemistry/ghb.html
4-methyl-GHB:https://www.thevespiary.org/rhodium/Rhodium/chemistry/4-methyl-ghb.html
MAB and DABD:https://www.thevespiary.org/rhodium/Rhodium/chemistry/mab.dabd.html
Articles and Arguments For and Against GHBPost 412696 (missing)
(runne: "Great article of GHB.", General Discourse)One of the best write-ups I have personally EVER seen (thanks pharmacist):Post 403259 (missing)
(pHarmacist: "Thruth About GHB! -DEA, Give Up, you Look Stupid!", General Discourse)Five part Article:Post 405869 (missing)
(raffike: "LOTS of info about GHB", General Discourse)Post 405870 (missing)
(raffike: "In his 1969 review on GHB, anaesthesiologist...", General Discourse)Post 405871 (missing)
(raffike: "Mamelak has also noted the unique ability of...", General Discourse)Post 405872 (missing)
(raffike: "GHB has been shown to induce major increases...", General Discourse)Post 405873 (missing)
(raffike: "In the course of mitochondrial ATP bioenergy...", General Discourse)Post 317348 (missing)
(Chromic: "GHB: Wernicke-Korsakoff syndrome", General Discourse)Post 317402 (missing)
(placebo: "Alternative names: Korsakoff psychosis; alcoholic ...", General Discourse)Post 435795 (missing)
(Rhodium: "Therapeutic GHB does not cause withdrawal", General Discourse)http://www.projectghb.org/while_sleeping/sld001.htm
Addiction to GHB:http://www.erowid.org/chemicals/ghb/ghb_addiction2.pdf
Pharmacologyhttps://www.thevespiary.org/rhodium/Rhodium/pharmacology/index.html
(look under the GHB heading)
Post 275360 (missing)
(Rhodium: "Re: DopamineReplenishment", General Discourse)Same as above:https://www.thevespiary.org/rhodium/Rhodium/pharmacology/ghb/ghb.a.new.and.novel.drug.of.abuse.pdf
Dosage:Post 257448 (missing)
(MaDMAx: "Re: GHB vs GBL 
", Newbee Forum)THF contamination and its toxicityPost 490525 (missing)
(7is: "Pharmacology of Tetrahydrofuran", General Discourse)Post 499157 (missing)
(jsorex: "Copyright © 1996 American Academy of Neurology", General Discourse)Wanted References of Relevance:Gouesnard, Jean-Paul; BSCFAS; Bull.Soc.Chim.Fr.; FR; 1; 1989; 88-94 (GHB from GABA)
Tetrahedron Lett. 1968, page 5819; Tetrahedron 1971,vol 27, page 2671References for Various Oxid. Reagents for use on THF:Post 67703 (missing)
(SpicyBrown: "Re: New(?) angle on THF > GBL", Chemistry Discourse)
