I was looking for perhaps some input from someone with some actual experience with this issue
And what is that supposed to mean?
man i told you the answer, DCM is better but xylene will still do the job, but you have to do more extractions, as indole has confirmed what i have said...
I cant speak for indole but as for me that IS coming from someone with exp in the field...
So, just for clarity....
I have so far said:
add plenty of NP and agitate, and do several extractions, pool and evap solvent
and then again:
make sure you do several more extraction washes than normal, this will be sure to counteract any solubility differnces....
Do you need it said AGAIN?
Well here it is....
DCM is better than Xylene (in this case), solubility ratio yes will be different but the main point of DCM's use is to allow easier seperation as (once again) indole has confirmed... if you cant find DCM (and god only knows why not) xylene will do but use more volume of NP and do several more washes and make sure to agitate plenty and let it settle before seperation.
-AC