Arylation and 1-Alkenylation on ?-Position of Ketones via Tributyltin Enolates Catalyzed by Palladium Complex
Masanori Kosugi, Isao Hagiwara, Takao Sumiya. and Toshihiko Migita
Bull. Chem. Soc. Jpn. 57, 242-246 (1984) (https://www.thevespiary.org/rhodium/Rhodium/pdf/arylation.isopropenylacetate.pd-busnome.pdf)
(https://www.thevespiary.org/rhodium/Rhodium/pdf/arylation.isopropenylacetate.pd-busnome.pdf)
Abstract
The reaction of tributyltin enolates, prepared from tributyltin methoxide and enol acetates in situ, with aryl and 1-alkenyl bromides in the presence of dichlorobis(tri-o-tolylphosphine)palladium was found to give ?-aryl and ?-(1-alkenyl)ketones, respectively, in good yields with essentially complete retention of the enol acetate regiochemistry.