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Author Topic: Pharmacologically interesting piperazines  (Read 2413 times)

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Barium

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Pharmacologically interesting piperazines
« on: January 10, 2003, 02:01:00 PM »
The piperazine family can, perhaps, be a fertile soil to explore.

Patent US6172229



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Lilienthal

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Only if you are interested in neuroleptics...
« Reply #1 on: January 10, 2003, 02:59:00 PM »
Only if you are interested in neuroleptics...  :)  Or am I missing something?
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Barium

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Considering the dopamine/noradrealine ...
« Reply #2 on: January 10, 2003, 03:46:00 PM »
Considering the dopamine/noradrealine releasing effect of 1-benzylpiperazine and the wierd serotonergic effect of 1-(3-trifluorophenyl)piperazine, I´m pretty sure there might be a few hidden treasures within the piperazine family.
Also, in the patent above, on page 2, there is also mentioned something about a japanese patent regarding m-trifluoromethylphenyl benzyl piperazines having analgetic and tranqualizing properties. Might come handy when the voices in the head becomes too loud and annoying.  ;)

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Aurelius

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Barium
« Reply #3 on: January 10, 2003, 05:34:00 PM »
Hey Barium, would you be interested in having that text typed/posted?  don't want to do it if nobody's interested.
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