Dear bees! Look at the nice patent I've found searching the Espacenet database. Our dear Alexander Shulgin describes preparation of various 4-alkyl-dialkoxy-amphetamines and their effect on animals.Patent US3547999
4-alkyl-dialkoxy-alpha-methyl-phenethylamines and their pharmacologically acceptable saltsAbstract: 4-alkyl-di(lower alkoxy)-
alpha- methylphenethylamines wherein alkoxy occupies one pair of the 2,5 and 2,6 positions on the benzene ring and alkyl is from 1 to 6 carbon atoms, inclusive, and the pharmacologically acceptable salts of such amines. These compounds affect the nervous system of vertebrates and are particularly adapted to be employed for the study of the depressant and stimulant activity of drugs upon the central nervous system of animals.
Phenethylamines of the present invention include:2,6-dimethoxy-
alpha,4-dimethyl-PEA;
2,5-diethoxy-
alpha,4-dimethyl-PEA;
2,6-diethoxy-
alpha,4-dimethyl-PEA;
2,5-dibutoxy-
alpha,4-dimethyl-PEA;
2,6-dipropoxy-
alpha,4-dimethyl-PEA;
4-ethyl-2,5-dimethoxy-
alpha-methyl-PEA (DOET)
4-ethyl-2,6-dimethoxy-
alpha-methyl-PEA
4-ethyl-2,5-diethoxy-
alpha-methyl-PEA
4-ethyl-2,6-diethoxy-
alpha-methyl-PEA
2-methoxy-6-ethoxy-
alpha,4-dimethyl-PEA
2-methoxy-5-ethoxy-
alpha,4-dimethyl-PEA
2-ethoxy-5-methoxy-
alpha,4-dimethyl-PEA
4-ethyl-2-methoxy-6-ethoxy-
alpha-methyl-PEA
4-ethyl-2-methoxy-5-ethoxy-
alpha-methyl-PEA
4-ethyl-2-ethoxy-5-methoxy-
alpha-methyl-PEA
4-butyl-2,5-dimethoxy-
alpha-methyl-PEA
4-hexyl-2,6-diethoxy-
alpha-methyl-PEA
4-propyl-2,6-dibutoxy-
alpha-methyl-PEA
4-pentyl-2,5-dipropoxy-
alpha-methyl-PEA
2-butoxy-5-methoxy-
alpha,4-dimethyl-PEA
4-butyl-2,6-dibutoxy-
alpha-methyl-PEA
4-hexyl-2,5-dimethoxy-
alpha-methyl-PEA
4-propyl-2,5-dimethoxy-
alpha-methyl-PEA
