PPA syrup extraction help needed

[patrick]

I have found a very interesting product: a dog incontinence syrup. It is easily available in europe.

This syrup contains the following:

1 ml enthält
Phenylpropanolamini hydrochloridum   50 mg 
Excip. ad solutionem

The syrup is sold as 100ml bottles.

Do somebody know the nature of the Excipient. If we have sugar, do you know how to extract the PPA. Is sugar soluble in alcohol?

[markus81245]

hey patrick, im markus and i come from germany and have read your post. with google you can find something about ppa.

how affect ppa. can you tell me more? and whats about the  sugar...you wanna take off it ?

thank you...markus

[markus81245]

i have found an interesting link...

http://www.erowid.org/chemicals/4_methylaminorex/4_methylaminorex_faq.shtml

[roger2003]

Title:  Phenylpropanolamine
CAS Registry Number:  14838-15-4
Derivative Type:  Hydrochloride
CAS Registry Number:  154-41-6
Trademarks:  Kontexin (Pharmacia & Upjohn);  Monydrin (Draco);  Obestat (Lemmon);  Propadrine (Merck & Co.)
Properties:  Crystals, mp 190-194°.  Odor resembling that of crude benzoic acid.  pKa 9.44±0.04.  Freely sol in water, alcohol.  Practically insol in ether, chloroform, benzene.  The aq soln is neutral to litmus.  LD50 orally in rats:  1490 mg/kg (Goldenthal).
Melting point:  mp 190-194°
pKa:  pKa 9.44±0.04

[Belial]

Can you tell us all of the inactives in the syrup? Then perhaps a better answer can be provided.

If you are pioneering the first thing to do would be an A/B extraction, making sure to wash the syrup with the NP solvent prior to extraction.