Author Topic: Ok Guru's, answer this one......  (Read 3822 times)

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honeysolution

  • Guest
Other impurities
« Reply #20 on: May 25, 2004, 06:34:00 PM »
It is true that all reactions should be cleaned up afterwards. And shit in = shit out, no matter which way you wanna reduce it. (So clean ephedrine is better, with less impurities to be reduced)
Something that I have found however, is that NONE of the articles I have read about performing birch reactions discuss over reduction, which is highly possible - considering that none of them give a method for weighing Lithium/sodium/alkali metal to the accuracy required (not easy to weigh something that is so reactive). You put in too much lithium (or whatever metal u choose), you'll end up with di-meth.
It seems to me that perhaps it would be better to add just a bit too little - end up with some unreduced ephedrine - and seperate the mix?

Red_Crown

  • Guest
over-reduction =/= alkylation
« Reply #21 on: June 02, 2004, 08:56:00 PM »

Something that I have found however, is that NONE of the articles I have read about performing birch reactions discuss over reduction, which is highly possible - considering that none of them give a method for weighing Lithium/sodium/alkali metal to the accuracy required (not easy to weigh something that is so reactive). You put in too much lithium (or whatever metal u choose), you'll end up with di-meth.



Forgive and correct me if I'm wrong, but:
How would adding too much lithium thus over-reducing take methamphetamine -> dimethamphetamine? Mustn't it be some other pathway if possible at all, since methamphetamine to dimethamphetamine is not reduction but alkylation?

Essentially- What the fuck are you talking about?