The Vespiary
The Hive => Newbee Forum => Topic started by: WHITE_DEVIL on November 19, 2002, 09:59:00 AM
-
sodium added to ethanol creates sodium ethoxide.
can this be done with any other alcohols?
Methanol?
-
...
"Turn on, Tune in and Drop Out"
-
Thanks
is it possible to make 'sodium methoxide' and use this turn say, 2,5 di bromo benzaldehyde to 2,5 dimethoxy benzaldehyde (+ 2NaBr)
Also can this be done with other group 1 metals such as Li?
-
...
"Turn on, Tune in and Drop Out"
-
are used for transethylation of ester groups. Free hydroxy groups will not be methylated. Maybe you could use a quartenary ammonium salt for that?
It is good to have an end to journey toward;
but it is the journey that matters, in the end.
-
And there is sodium isopropoxide aswell
A friend with speed is a friend indeed
-
You could protect the aldehyde function of 2,5-dibromobenzaldehyde as the acetal, then react it with an excess of sodium methoxide in methanol using a catalytic amount of Copper(I)bromide, followed by hydrolysis of the acetal to get 2,5-dimethoxybenzaldehyde.
Both instructions for acetal formation and methoxylation can be found at my page, but exemplified for 3,4,5-trimethoxybenzaldehyde and 5-bromovanillin respectively.