Here are the claims of the patent. I warn you that I don’t understand Czech good enough, so there might bee colossal mistakes in this translation. Italics are my comments.
1. Claims the preparation of substituted amides of the d-lysergic and d-dihydrolysergic acid and their derivates like shown on the structure I ( just a (dihydro)lysergic- amide-NR1R2 structure, see in the patent),
where
R1 - means a H atom, alkyl group with 1 to 4 carbon atoms or a 1-hydroxy-2-alkyl group with 2 to 4 carbons,
R2 - means a H atom, alkyl group with 1 to 2 carbon atoms, aryl group with 6 atoms in the ring or the group –(CH2)n-N(R5R6), where R5 and R6 is an alkyl with 1 to 3 carbon atoms, n is a full number from 1 to 5,
R3 - means a H atom, alkyl group with 1 to 4 carbon atoms or some alkenyl group with 2 to 4 carbon atoms (this is just the substituent on the basic N which is methyl in lysergic acid)
R4 - means a H atom, alkyl group with 1 to 4 carbon atoms (this is just the substituent on the indolic N which is hydrogen in lysergic acid)
x-y – means a single or double bond
and their pharmaceutically useful addition salts with organic or inorganic acids, therefore claiming, that compounds of the structure II wherein
R3, R4 and x-y are like described in the above list
condense with the amino compounds of the structure III (R1R2NH)
wherein the R1 and R2 are already described in the above list,
in the presence of a base, organic solvent and the condensation reagent propylphosphate acid anhydride of the structure IV
where m>3.
2. …that the condensing reagent of the structure IV is used in the form of a solution in an organic solvent.
3. …that the solvent used is taken from the group composed of ethylacetate, toluene, DCM, DMF, acetone, CHCl3, THF, dioxane or a mixture of whichever of these.
4. …that the base used is taken from the group composed of pyridine, N-ethylpiperidine, triethylamine, hydroxide [draselnym?] (probably potassium?), NaOH, anhydrous potassium(?) carbonate or anhydrous sodium carbonate.
5. …that the reaction between compounds described with the structure II and the amine described by the structure III is performed at the temperature from -10°C up to 130°C or at the boiling temperature of the solvent.