and the chlorophylls should have been extracted with the water extraction.
The chlorophylls will neutralize your toluenesulphonic acid; perhaps this is why you need such a large amount. Better to remove the chlorophylls before attempting the acid catalyzed condensation/isomerization.
There are many ways to do this (and maybe Adams didn't know all of them :), but could you point out a reference stating that glacial acetic acid/sulfuric acid produces THC acetate?
No but as being a chemistry major for the last two years you may just have to take my word for it. I have also done plenty of research for my school in the organic lab since that is a sort of specialty. I would say look up Fisher esterification on the web you may learn something.
Terbium, the chlorophylls are taken' out with the water wash after the protonation reaction with the organic acid in the first step. There is no need to take out the chlorophylls in the first extraction. If you want to take them out then do it as you say. The final product will be the same. The product was cleaned before the esterification from all water solubles.
At the present this pretty oil has a nice reddish amber color and [sniff] mmmmmmm[/sniff] has a real nice smell.
http://www.chemhelper.com/fischester.html (http://www.chemhelper.com/fischester.html)
This seems to be some toluene dissolved acetate salt. It's highly unlikely that acetylation would make the extremely lipophilic cannabinoid more water soluble.
Without chromatography one is not going to produce a pure compound even with butane or hexane. It was not the point to make a pure compound also. If one wanted to make a purer compound then indeed it seems the ever consistent lughs method would be adhered too but it wasn’t but not without knowing of this method mind you. One can believe that a alcohol such as THC is responsible for the entire high from cannabis but as is known cannabis and related plants contain more than the alkaloids hordenine and piperidine which if you don’t know are moieties of morphine which some find in hops plants ironically, a marijuana relative. Maybe you will understand now why the cyclo alcoholic ethers were not specifically extracted from the cannabis; it just wasn’t pertinent to the agenda you see. Your intelligence and thoughtfulness is appreciated though mind you. With chromatography one could achieve a pure compound from the first effort. The compound/s was/were brought through a TLC plate to find a small amount of dark impurity but as for the largest amount being the lighter colored oil compound/solution. The burn test revealed a small amount of charcoalic residue but alas there was no NaOAc residue. Seems a DCM/hexane on silica jel column chromatography would have been ideal but kitchen chemistry wasn’t for it.
I have also done plenty of research for my school in the organic lab since that is a sort of specialty. I'm a senior and a chem major at one of the top 10 science programs in the US. NO WAY is a sophomore doing research for a university. The very idea is laughable. Did you post references for this reaction, or is this all your own work?
Well indeed research had been done all through Organic Chemistry II in which aminic lipids were formed that were meant to be tested as synthetic glucose passage ways for diabetes patients. Apparently what the lipids would do is form a channel into the cell in which glucose could bind to in order to transport across the lipid bilayer. If you do not know, some diabetes patients do not have the amount of glucose channels necessary for proper glucose transport into the cell that is where these lipids came into play.
Some time ago a book was read called Cannabis alchemy in which they formed the ester by reaction with acetic acid. Apparently they thought the acetic acid was enough of a catalyst to form the ester but alas it was figured that a small amount of ACS reagent grade H2SO4 would suffice to shorten the reaction time. The book was read but having been a long time since that time, memory was all there was to go by you see. That could be one reason why the amounts of reagents and reflux times were a little off. No mas’ don’t beat em’ It won’t happen again.
As for laughing at this presence, it wouldn’t be the first time. References aren’t needed all the time asshole.
https://www.rhodium.ws (https://www.rhodium.ws)