The Vespiary

The Hive => Methods Discourse => Topic started by: Aurelius on May 12, 2004, 09:50:00 PM

Title: PCP and Relatives: A Synthetic View
Post by: Aurelius on May 12, 2004, 09:50:00 PM
Bear with me, this is a completely new project and I've got hundreds of links to put in.  I'm very busy and this might take a few weeks or longer- but it's a popular enough topic that I thought it would be worth it.

PCPstraight-up

https://www.thevespiary.org/rhodium/Rhodium/chemistry/pcp.shulgin.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/pcp.shulgin.html)


https://www.thevespiary.org/rhodium/Rhodium/chemistry/pcp/cn_synth.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/pcp/cn_synth.html)


Post 288137 (https://www.thevespiary.org/talk/index.php?topic=11815.msg28813700#msg28813700)

(Antoncho: "A cool PCP synthesis", Novel Discourse)

Ideas on PCP Synthesis:

Post 475464 (https://www.thevespiary.org/talk/index.php?topic=11492.msg47546400#msg47546400)

(ning: "phencyclidine sans cyclohexanone", Novel Discourse)

Analogues:

PCPy: Pyrrolidene analogue:

Post 101681 (missing)

(The Alchemist: "Dust for the masses...", Chemistry Discourse) (read the whole thread)

4-MeO-PCP

https://www.thevespiary.org/rhodium/Rhodium/chemistry/4-meo-pcp.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/4-meo-pcp.html)



Fluorinated Analogues:

Post 471106 (https://www.thevespiary.org/talk/index.php?topic=9657.msg47110600#msg47110600)

(Rhodium: "Fluorinated PCP Analogs", Methods Discourse)

Contaminants:

Post 382798 (https://www.thevespiary.org/talk/index.php?topic=9657.msg38279800#msg38279800)

(Rhodium: "PCP byproducts", Methods Discourse)

https://www.thevespiary.org/rhodium/Rhodium/chemistry/pcp.pcc.analysis.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/pcp.pcc.analysis.html)


Post 406851 (https://www.thevespiary.org/talk/index.php?topic=9468.msg40685100#msg40685100)

(Rhodium: "Measuring PCC contamination of PCP", Methods Discourse) (same as above page)

Post 502110 (https://www.thevespiary.org/talk/index.php?topic=9468.msg50211000#msg50211000)

(Rhodium: "Pyrolytic Fate of the PCP contaminant PCC", Methods Discourse)

TCP

Post 484668 (https://www.thevespiary.org/talk/index.php?topic=9466.msg48466800#msg48466800)

(Xicori: "TCP Synthesis", Methods Discourse)
Bioassays

Post 486907 (https://www.thevespiary.org/talk/index.php?topic=9466.msg48690700#msg48690700)

(Xicori: "Bioassay", Methods Discourse)

Contamination
PCC Detection

https://www.thevespiary.org/rhodium/Rhodium/chemistry/pcp.pcc.analysis.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/pcp.pcc.analysis.html)



PCDE

Synth and Bioassay

Post 369598 (https://www.thevespiary.org/talk/index.php?topic=11834.msg36959800#msg36959800)

(Antoncho: "Zealot: synthesis and bioevaluation of PCDE", Novel Discourse)

PCM

Post 475049 (https://www.thevespiary.org/talk/index.php?topic=9719.msg47504900#msg47504900)

(Xicori: "PCM synthesis", Methods Discourse)
Bioassay

Post 475116 (https://www.thevespiary.org/talk/index.php?topic=9719.msg47511600#msg47511600)

(Xicori: "thanks for the flowers :-D details on bioassay", Methods Discourse)

Ketamine

https://www.thevespiary.org/rhodium/Rhodium/chemistry/ketamine.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/ketamine.html)


https://www.thevespiary.org/rhodium/Rhodium/chemistry/ketamine2.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/ketamine2.html)



analogues:

Post 465673 (https://www.thevespiary.org/talk/index.php?topic=11579.msg46567300#msg46567300)

(Manichi: "Discussion on possible ketamine analogs", Novel Discourse)

Post 505521 (https://www.thevespiary.org/talk/index.php?topic=12086.msg50552100#msg50552100)

(ning: "Modified ketamine method", Novel Discourse)

Refs:If the refs aren't here in this digest  or elsewhere at the Hive (so do a search), they would be appreciated.

Post 466915 (https://www.thevespiary.org/talk/index.php?topic=11579.msg46691500#msg46691500)

(Manichi: "Ketamine References Feeding", Novel Discourse)

Post 466993 (https://www.thevespiary.org/talk/index.php?topic=11579.msg46699300#msg46699300)

(Rhodium: "Ketamine Reference Feeding #2", Novel Discourse)

Tiletamine (SP?)

Eticylclidine

https://www.thevespiary.org/rhodium/Rhodium/chemistry/eticyclidine.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/eticyclidine.html)



Rolicylidine

https://www.thevespiary.org/rhodium/Rhodium/chemistry/eticyclidine.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/eticyclidine.html)




Others?

Please feel free to pm links, comments, suggestions etc. to Aurelius on this Digest or any others maintained by me.

MISC TO BE PLACED:

Post 455365 (https://www.thevespiary.org/talk/index.php?topic=8906.msg45536500#msg45536500)

(Bwiti: "Novel Phenylcyclohexylamines..", Methods Discourse)

Post 424992 (https://www.thevespiary.org/talk/index.php?topic=9898.msg42499200#msg42499200)

(Bwiti: "1-(1-Phenylcyclohexyl)-4-phenylpiperidine", Methods Discourse)

Patents:
contributed by Cyrax in:

Post 356567 (https://www.thevespiary.org/talk/index.php?topic=9657.msg35656700#msg35656700)

(Cyrax: "PCP Patents, a compendium", Methods Discourse)

Patent GB836083 (http://l2.espacenet.com/dips/viewer?PN=GB836083&CY=gb&LG=en&DB=EPD)


Patent GB837747 (http://l2.espacenet.com/dips/viewer?PN=GB837747&CY=gb&LG=en&DB=EPD)


Patent US2921076 (http://l2.espacenet.com/dips/viewer?PN=US2921076&CY=gb&LG=en&DB=EPD)


Patent US3097136 (http://l2.espacenet.com/dips/viewer?PN=US3097136&CY=gb&LG=en&DB=EPD)


Patent US3145229 (http://l2.espacenet.com/dips/viewer?PN=US3145229&CY=gb&LG=en&DB=EPD)


Patent US5248686 (http://l2.espacenet.com/dips/viewer?PN=US5248686&CY=gb&LG=en&DB=EPD)




Contributed by Bwiti in:

Post 357544 (https://www.thevespiary.org/talk/index.php?topic=9657.msg35754400#msg35754400)

(Bwiti: "That's good news!", Methods Discourse)

Patent GB758143 (http://l2.espacenet.com/dips/viewer?PN=GB758143&CY=gb&LG=en&DB=EPD)


Patent GB838748 (http://l2.espacenet.com/dips/viewer?PN=GB838748&CY=gb&LG=en&DB=EPD)


Patent GB853775 (http://l2.espacenet.com/dips/viewer?PN=GB853775&CY=gb&LG=en&DB=EPD)


Patent GB861350 (http://l2.espacenet.com/dips/viewer?PN=GB861350&CY=gb&LG=en&DB=EPD)


Patent US3192219 (http://l2.espacenet.com/dips/viewer?PN=US3192219&CY=gb&LG=en&DB=EPD)


Patent US3097207 (http://l2.espacenet.com/dips/viewer?PN=US3097207&CY=gb&LG=en&DB=EPD)

 

Patent GB836083 (http://l2.espacenet.com/dips/viewer?PN=GB836083&CY=gb&LG=en&DB=EPD)

 

Patent GB837747 (http://l2.espacenet.com/dips/viewer?PN=GB837747&CY=gb&LG=en&DB=EPD)

 

Patent US5969159 (http://l2.espacenet.com/dips/viewer?PN=US5969159&CY=gb&LG=en&DB=EPD)

 

Patent US3097136 (http://l2.espacenet.com/dips/viewer?PN=US3097136&CY=gb&LG=en&DB=EPD)


Patent US3145229 (http://l2.espacenet.com/dips/viewer?PN=US3145229&CY=gb&LG=en&DB=EPD)


Patent US3097136 (http://l2.espacenet.com/dips/viewer?PN=US3097136&CY=gb&LG=en&DB=EPD)


Patent US3247200 (http://l2.espacenet.com/dips/viewer?PN=US3247200&CY=gb&LG=en&DB=EPD)


Patent US3522273 (http://l2.espacenet.com/dips/viewer?PN=US3522273&CY=gb&LG=en&DB=EPD)


Patent US2921076 (http://l2.espacenet.com/dips/viewer?PN=US2921076&CY=gb&LG=en&DB=EPD)


Patent US3254124 (http://l2.espacenet.com/dips/viewer?PN=US3254124&CY=gb&LG=en&DB=EPD)



References Requested Specifically for this Digest:

Post 361229 (https://www.thevespiary.org/talk/index.php?topic=9657.msg36122900#msg36122900)

(Bwiti: "Needed References", Methods Discourse)
(before sending of these refs- be sure that they haven't already been posted here or in posts subsequent to 361229 in that same thread)

Post 361271 (https://www.thevespiary.org/talk/index.php?topic=9657.msg36127100#msg36127100)

(Rhodium: "More PCP", Methods Discourse)

Post 378784 (https://www.thevespiary.org/talk/index.php?topic=9657.msg37878400#msg37878400)

(Rhodium: "Rigid PCP Analogs - Binding to Sigma/PCP receptors", Methods Discourse)

Mostly Pharm info, but some synth:

Post 507205 (https://www.thevespiary.org/talk/index.php?topic=9657.msg50720500#msg50720500)

(7is: "More PCP related studies", Methods Discourse) -- be sure to check the following threads also.

Precursors
Cyclohexanone
by ox. of Cyclohexanol
with KMnO4

Post 285993 (https://www.thevespiary.org/talk/index.php?topic=9759.msg28599300#msg28599300)

(Elementary: "Oxidation of cyclohexanol with KMnO4", Methods Discourse)

1,5-Dibromopentane:

Post 436097 (https://www.thevespiary.org/talk/index.php?topic=9620.msg43609700#msg43609700)

(pHarmacist: "1,5-dibromopentane", Methods Discourse)

Post 288137 (https://www.thevespiary.org/talk/index.php?topic=11815.msg28813700#msg28813700)

(Antoncho: "A cool PCP synthesis", Novel Discourse)

Post 184706 (https://www.thevespiary.org/talk/index.php?topic=11635.msg18470600#msg18470600)

(Rhodium: "Re: Help to make 1,5-dibromopentane (Method). for PCP", Novel Discourse)

PCA:

Post 105162 (missing)

(Slappy: "Re: PCA question", Chemistry Discourse)


PCC: 1-Piperidinyl Cyclohexanecarbonitrile (& analogues)

Post 172690 (missing)

(slappy: "Re: Weight of PCC-Analogue(from methylamine).....", Chemistry Discourse)

Post 101408 (missing)

(Beagle: "Re: Question about 1-piperidine-carbonitrile...", Chemistry Discourse)

--

Post 465740 (https://www.thevespiary.org/talk/index.php?topic=11579.msg46574000#msg46574000)

(josef_k: "phenylcyclopentylketone", Novel Discourse)

Post 465792 (https://www.thevespiary.org/talk/index.php?topic=11579.msg46579200#msg46579200)

(Manichi: "Cyclohexene -persulfate/CuSO4->CyclopentaneCOOH", Novel Discourse)

Post 466155 (https://www.thevespiary.org/talk/index.php?topic=11579.msg46615500#msg46615500)

(Vitus_Verdegast: "Great work Manichi!!", Novel Discourse)