Synthesis of Amides of Lysergic Acid
William L. Garbrecht
J. Org. Chem. 24, 368-372 (1958) (https://www.thevespiary.org/rhodium/Rhodium/pdf/lsd.garbrecht.pdf)
(https://www.thevespiary.org/rhodium/Rhodium/pdf/lsd.garbrecht.pdf)
Abstract
Although interest in the chemistry and pharmacology of lysergic acid derivatives has remained high for many years, until recently only one useful method for converting lysergic acid into its amide derivatives has been recorded. This method as described by A. Stoll consists of cleaving ergot alkaloids with hydrazine. The resulting lysergic acid hydrazide on treatment with nitrous acid is converted into the azide which may be used to prepare the desired amide by acylation of an appropriate amine.
Also, some further info on this synth can be found in https://www.thevespiary.org/rhodium/Rhodium/chemistry/psychedelicchemistry/chapter7.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/psychedelicchemistry/chapter7.html)