The Vespiary

The Hive => Methods Discourse => Topic started by: Rhodium on September 03, 2002, 12:35:00 AM

Title: NaBH4/NiCl2 reduction of arylacetonitriles to PEAs
Post by: Rhodium on September 03, 2002, 12:35:00 AM

https://www.thevespiary.org/rhodium/Rhodium/chemistry/nitrile2amine.nickelboride.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/nitrile2amine.nickelboride.html)

Title: interesting that no sonication necessary
Post by: starlight on September 03, 2002, 11:30:00 AM

whereas sonication was necessary to get decent yields when reducing P2NPs.

Are nitriles easier to reduce than nitropropenes?

Or is it using dry reagents for the reaction?

Or both?

Title: Nitriles are much easier to reduce than ...
Post by: Rhodium on September 03, 2002, 12:50:00 PM

Nitriles are much easier to reduce than nitroalkenes.