The Vespiary

The Hive => Methods Discourse => Topic started by: psytech on November 07, 2002, 04:51:00 PM

Title: help quick, does MDA freebase float
Post by: psytech on November 07, 2002, 04:51:00 PM
SWIM just completed a MDA from Bromosafrole using PTC and an azide intermediate RNX.Their freebase doesnt fall out, does it float,they have this tan mass floating in basic h2o, its not an oil.Ps i have used the FSE
Title: MDA freebase density
Post by: Rhodium on November 07, 2002, 04:55:00 PM
Yes, I think MDA freebase will float on water. Now extract that basic aqueous solution with ether or DCM, dry the pooled organic layers, evaporate the solvent and distill the MDA freebase under vacuum. The boiling point is 80-90°C at 0.2mmHg.
Title: Ekstract with something (DCM,Toluen wath ever) ...
Post by: hest on November 07, 2002, 04:57:00 PM
Ekstract with something (DCM,Toluen wath ever) then wash repet the A/B wash. Sounds like a not so pure product.
Title: got it
Post by: psytech on November 07, 2002, 05:06:00 PM
Basic solution i being extracted with toulene, has a nice brownish color to it, will re a/b, extract with DMC, distill.  :P
Title: All the MDX intermediates and freebases have a ...
Post by: Osmium on November 11, 2002, 04:06:00 AM
All the MDX intermediates and freebases have a higher density than water!
But since your stuff floated on water containing other stuff it's impossible to say if it will float or not.
Also, impure chems can have a wildly differing density, so this is usually not a reliable test for identity.

I'm not fat just horizontally disproportionate.