Nitro alkEne direct to amine !?!?!
Have been gone awhile and what do I find at Rhodium, nitro-alkene direct to amine!
See “Reduction of Nitroalkenes and Nitroalkanes to Amines Using NaBH4/NiCl2 and Ultrasound” at Rhodium
The only time I have heard of such an OTCish method it was some low yielding electro chem divided cell head-ache.
I tried a few key words in the search engine but failed to see any discussion on this method. So I have some questions (three really), maybee some bee may have some thoughts.
OK so think TMA-2,
1. In the article they use 1-nitro-cyclohexene (BTW, WTF is the diff between that and 1-nitro-cyclohex-1-ene (see article reactant table)) not exactly TM-nitropropenes twin. Any bee care to speculate how the nitrosytrene of asarone would act in this situation?
2. The article lacks any detail concerning the sonication, I wonder if an ultrasonic jewelry cleaner would do the trick? Any thoughts?
3. So from vac distilled Indian calamus oil,
Nitroalkenes from Alkenes using NaNO2/I2/Ethylene Glycol (see Rhodium)
and then,
Reduction of Nitroalkenes and Nitroalkanes to Amines Using NaBH4/NiCl2 and Ultrasound (see Rhodium)
catch my drift?
Any thoughts are greatly appreciated!
