Author Topic: Melatonin Hydrolysis  (Read 4964 times)

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Melatonin Hydrolysis
« on: November 04, 2003, 10:44:00 PM »
I believe I have read all posts pertaining to this but am still not clear.

When hydrolysing N-Acetyl-5-Methoxytryptamine (melatonin) to 5-Methoxytryptamine, the Sodium Dithionite and the Nitrogen atmosphere is used to prevent oxidation, right?

SWIM has large amounts of melatonin and can afford a loss in yeild. Could some one explain to me what would happen if I was to reflux melatonin with NaOH only?


  • Guest
« Reply #1 on: November 12, 2003, 11:24:00 AM »
You already answered your question yourself!  :)

dithionite is easy to obtain, used for reducing indigo etc.. eg. go to your local art supply store.
UTFSE for OTC uses for it.


  • Guest
« Reply #2 on: November 16, 2003, 08:01:00 PM »