The Vespiary

The Hive => Newbee Forum => Topic started by: slackdaddy on January 12, 2004, 09:03:00 AM

Title: Denatured alcohol in Al/Hg/HOAc Oxime redxn?
Post by: slackdaddy on January 12, 2004, 09:03:00 AM

Swim doesn't currently have any 95% ethanol. But swim can get denatured alcohol (from the big blue store).  If swim substitutes this in the Al/Hg/HOAc Oxime reduction, will there be any problems?

Swim is assuming there will be none, but after UTFSE, swim still figured he would ask if anyone has had any problems with the denatured stuff.

Thanks,
Slack :)

Title: Not sure about the oxime...
Post by: pyroflatus on January 12, 2004, 04:28:00 PM

I don't know about the sensitivity of the oxime reduction, but as per

Osmium's suggestion (https://www.thevespiary.org/rhodium/Rhodium/chemistry/alhg.osmium.html)

(https://www.thevespiary.org/rhodium/Rhodium/chemistry/alhg.osmium.html), denatured alcohol works well for Al/Hg reductions. For the hell of it, I refluxed some denatured ethanol over CaO (this hadn't been denatured with methanol) and distilled it to compare it with denatured alcohol for reductive aminations, and no discernable difference was observed.