Eur. J. Med. Chem. 37 (2002) 527–539
Invited Review
Arylethylamine psychotropic recreational drugs: a chemical
perspective
Sally Freeman a,*, John F. Alder b
a School of Pharmacy and Pharmaceutical Sciences, Uniersity of Manchester, Oxford Road, Manchester M13 9PL, UK
Department of Instrumentation and Analytical Science, UMIST, Manchester M60 1QD, UK
Received 18 April 2002
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Abstract
The arylethylamines substituted in the aryl ring, side-chain carbons and on the terminal amine, comprise a large number of human mood and behaviour altering chemicals. Some of these psychotropic drugs have been used since pre-history, but in many states are proscribed and are consequently subject to clandestine synthesis and illegal traffic world-wide in the forms particularly of amphetamines and to a lesser extent tryptamines. The chemistry employed in the synthesis of these compounds is dictated often by the available precursors and relies usually on relatively simple, unsophisticated conversion reactions to a suitable product. The internet web sites and documentation of the recreational drug culture have been studied alongside the professional scientific and
regulatory literature. The review demonstrates the great complexity of the chemistry and neuro-pharmacology of these chemicals and the challenge faced by legislative bodies to control their traffic and use for the sake of social welfare.
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I have the PDF here. Iff rhodium want it i'll mail it to him.
The hive and rhodium.ws is cited some times in the paper.
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