Hi,
I was looking at https://www.thevespiary.org/rhodium/Rhodium/chemistry/nitro2amine.zn-formate.html (https://www.thevespiary.org/rhodium/Rhodium/chemistry/nitro2amine.zn-formate.html)
where nitropropane was reduced using activated Zinc and Ammonium Formate. I know in Beakers 2CB synthesis something similar is used except the catalyst is Pd/C.
My questions:
1. Is it possible to use a nitroethane (a reduced nitrostyrene in my case) in place of the nitropropane?
2. If I were to use Potassium Formate instead of Ammonium formate would I have to adjust the amount the formate salt that would be added?
3. If the proceedure at the bottom the page is scaled up, at what temperature should I keep the reaction at? (like a 10x scale up).
Thank You for any help.