The Vespiary

The Hive => Tryptamine Chemistry => Topic started by: PolytheneSam on March 04, 2002, 02:42:00 AM

Title: Benzothiophene analogs
Post by: PolytheneSam on March 04, 2002, 02:42:00 AM

You can look up analogue here. 

http://www.m-w.com (http://www.m-w.com)

I found two articles in the Journal of Medicinal Chemistry on benzothiophene analogs of tryptamines.  They mention that the N-H in the indole ring in tryptamines aren't important in receptor binding.  They also give a synthesis of the dimethyltryptamine analog (S in place of N-H in the indole ring) from the tryptamine analog using formaldehyde and formic acid

Post 248013 (missing)

(PolytheneSam: "Re: Leuckart alkylation", Newbee Forum) .  Does anyone have any info about psychoactive properties?

1) Sept. 1968 pages 1049-1054
2) Vol. 13, No. 6, 1970, pages 1205-1208

Also see

http://us.f1.yahoofs.com/users/4212977f/bc/Leuckart+Reaction/Leuckart307.tif?bc_dtg8ARDFKndoC (http://us.f1.yahoofs.com/users/4212977f/bc/Leuckart+Reaction/Leuckart307.tif?bc_dtg8ARDFKndoC)

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