Usually the relative amount of solvents is drastically reduced during the upscaling of a reaction. The amount depends mainly on the solubility of the reactants and the consistency of the mixture.
For upscaling one usually starts with microreactions of 10 to 100 mg under TLC control to find out the reaction conditions. After optimization one goes stepwise to larger scales thereby eliminating problems due to the larger amounts (e.g. problems with stirring , heating, cooling, and purification).
The same is true for (column) chromatography. One starts with microgram amounts on thin-layer-chromatogryphy sheets (TLC) to find out the best solvent system, and then runs stepwise larger columns under (TLC-)control of your fractions.
It's impossible to get a reaction or a purification running on the first try on a larger scale with out this initial testing!!! You would be like a blind and deaf person in a new town...