The Vespiary

The Hive => Newbee Forum => Topic started by: EvilMadChemist on August 12, 2004, 11:23:00 PM

Title: HydroCodone -> OxyCodone?
Post by: EvilMadChemist on August 12, 2004, 11:23:00 PM
ive searched the search engine , cant find anything,  im wondering how hard would it be to convert HydroCodone to OxyCodone?
Title: Deoxygenation of a Tertiary Alcohol
Post by: Rhodium on August 13, 2004, 02:46:00 AM
(https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000525100-oxycodone.jpg)
Oxycodone

Hydrocodone has a structure very similar to the above - it just lacks the OH group in the 14-position.
However, I am not aware of any easy method which would be able to reduce that -OH to -H without at the same time messing up the ketone in the 3-position or any other unwanted mischief.

Title: Thanks Rhodium thats what i thought, i noticed
Post by: EvilMadChemist on August 13, 2004, 03:40:00 AM
Thanks Rhodium thats what i thought, i noticed they where the same structure beside the OH and H, but i was hoping there might been easy way for a newbee.