I've found some refs for ICE and a route like this:
On Beilstein (BRN 149933) there are 5 type of reactions; I've found that on Yakugaku Zasshi (a Japanese journal of pharmacological chemistry),
(1948),
68, 70 it is possible make ICE from 1,2-dibromo-1-phenylpropane (from propenylbenzene!) and urea.
Other refs are:
on the same journal,
(1978),
98(5), 611-617;
Heterocycles,
(1997),
6(9-10), 1604-9
Berichte,
(1931),
64, 1076-86 (in german!)
J. Med. Chem.,
(1963),
6, 266-72 (with CNBr, usual route)
On Chemical Abstract:
93:220636x --> Eur. J. Med. Chem. - Chem. Ther.,
(1980),
15(2), 111-17 (also this in german)
Unfortunately I cant achieve these refs and I dont know gernan, so I someone could please help me...
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