The Vespiary

The Hive => Methods Discourse => Topic started by: maxscorpio on September 09, 2003, 04:18:00 AM

Title: microwave safrole isomerization
Post by: maxscorpio on September 09, 2003, 04:18:00 AM

anybody tried a microwave for this. other than the huge amount of koh used, any drawbacks or problems for this method. i UTFSE, but came up with zero results strangely, are there any writeups other than rhodiums.
    This method sounds so quick with great yields.

Title: Microwave Isomerization of Allylbenzenes
Post by: Rhodium on September 09, 2003, 08:53:00 AM

Nothing in TFSE? A simple search for "isomerization microwave" gave among other things the following excellent threads:

Post 291995 (https://www.thevespiary.org/talk/index.php?topic=6476.msg29199500#msg29199500)

(foxy2: "Safrole Isomerization in microwave", Chemistry Discourse)

Post 108400 (missing)

(dormouse: "Microwave Isomerization of Safrole  - Cherrie Baby", Novel Discourse)

Post 162640 (missing)

(jimwig: "microwaves for honey", Methods Discourse)

Edit: New addition to my page:

Isomerization Of Safrole And Eugenol Under Microwave Irradiation

Synthetic Communications, 27(24), 4335-4340 (1997) (https://www.thevespiary.org/rhodium/Rhodium/chemistry/mw.isomerizafrole.html)

(https://www.thevespiary.org/rhodium/Rhodium/chemistry/mw.isomerizafrole.html)