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The Hive => Newbee Forum => Topic started by: EvilMadChemist on June 12, 2004, 07:52:00 AM

Title: Creating Salt from Extract of Amanita Muscaria
Post by: EvilMadChemist on June 12, 2004, 07:52:00 AM

once i let the Amanita Muscaria sit in Methanol, and filtered out all the junk. i was wondering about creating a salt from it , if anyone has, and how stable is it? im still a noob in the world of chemisty, this fall im taking Chemisty I. ive been reading a Organic Chemisty book. so im kind of still learning.

Title: Not that easy
Post by: Nicodem on June 12, 2004, 11:40:00 AM

Isolating muscimole from A. muscaria is very difficult. I can't imagine any trick that would help.
In the scientific literature it is done with a cromatographyc column.

Title: lets say , i didnt want to isolate the ...
Post by: EvilMadChemist on June 12, 2004, 03:17:00 PM

lets say , i didnt want to isolate the chemical its self , but  create a salt of just everything.

Title: Muscimol Tautomerism & Zwitterion Formation
Post by: Rhodium on June 12, 2004, 08:07:00 PM

Muscimol does not form salts very well, because while it is usually drawn as being an oxazol-3-one (top picture), this shape forces the molecule to have bonds of varying lenghts and that is very energetically unfavorable. The molecule solves this by moving the carbonyl double bond into the ring to give an aromatic oxazol-3-ol, and because this OH group is rather acidic, the proton will move to the aliphatic nitrogen, forming a zwitterion (a molecule having both positive and negative charges simultaneously).

(https://www.thevespiary.org/rhodium/Rhodium/hive/hiveboard/picproxie_docs/000512920-file_tyc2.gif)

Title: humm , so by creating a salt out of it , the...
Post by: EvilMadChemist on June 12, 2004, 09:49:00 PM

humm , so by creating a salt out of it , the yields would be low. and it wouldnt be an easy proccess for a noob to do?  i guess ill just get back to the books.

Title: Time for Flash Chromatography
Post by: Rhodium on June 13, 2004, 01:48:00 AM

humm , so by creating a salt out of it , the yields would be low.

...rather that a salt simply won't form.

and it wouldnt be an easy proccess for a noob to do?

You need to make a solvent extract and then purify this by column chromatography, a.a.

Flash Chromatography (https://www.thevespiary.org/rhodium/Rhodium/chemistry/equipment/flash.html)

(https://www.thevespiary.org/rhodium/Rhodium/chemistry/equipment/flash.html)

Title: Can ibotenic acid form salts?
Post by: wad on June 14, 2004, 01:06:00 PM

Can ibotenic acid form salts?

Title: i was reading this , and i found it quite...
Post by: EvilMadChemist on June 15, 2004, 07:12:00 PM

i was reading this , and i found it quite interesting

http://www.chem.ubc.ca/courseware/121/tutorials/exp3A/columnchrom/ (http://www.chem.ubc.ca/courseware/121/tutorials/exp3A/columnchrom/)

ive done a paper chromotograph before, but not for seperating, just to see what is in this mysterious mixture.