Author Topic: 2c-b -> dob ?  (Read 2078 times)

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Vaaguh

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2c-b -> dob ?
« on: October 10, 2002, 05:29:00 PM »
Do you guys think this would work ?



I am not sure if the Al/Hg will reduce the alkene producing a decent yield, should I consider using NaBH4 and Al/Hg for reducing ?


Rhodium

  • Guest
The dehydration of the intermediate nitroalkohol ...
« Reply #1 on: October 10, 2002, 05:54:00 PM »
The dehydration of the intermediate nitroalkohol to the nitroalkene won't happen without vigorous conditions, such as heating with phtalic anhydride, as the alkene isn't conjugated with the benzene ring. That step alone will be so low-yielding that the synthesis is of no use.

Start from scratch, that is much more plausible than this suggestion.

Alcohol, an unconsciousness-expanding drug

No1CockSucker

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Even furthermore.
« Reply #2 on: October 13, 2002, 11:54:00 PM »
2C-B + potassium permanganate --> 4-bromo-2,5-dimethoxy-benzoic acid.