Author Topic: Xylene,..substitute??? WTF!!  (Read 3164 times)

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  • Guest
Xylene,..substitute??? WTF!!
« on: July 07, 2003, 11:07:00 PM »
Have any bees ever heard of this or have any idea what the hell it is??

Xylene Substitute is a newly developed Xylene-free clearing agent. Unlike Xylene or Citrus Limonene, it has no overpowering odor. Use Xylene Substitute without any of the health concerns of Xylene. Xylene Substitute is completely soluble in alcohol and has no effect on most laboratory plastics. It is also less flammable than Xylene.

This Xylene replacement gives you excellent clinical results. Xylene Substitute evaporates quickly and is ideal for use with all Trichrome procedures. It gives consistent results with excellent clarity. Xylene Substitute effectively deparaffinizes and eliminates residual chemicals.

Xylene Substitute is convenient and is less expensive than Xylene. Most users will not require disposal by second party waste haulers. Costly distillation becomes unnecessary.



  • Guest
Lucky US customers!
« Reply #1 on: July 08, 2003, 03:13:00 AM »
No safety or tech data on the site yet. If it is the same as propar, it is propylene glycol ether.


  • Guest
I knew it
« Reply #2 on: July 08, 2003, 05:28:00 AM »
Ya know, I almost started a thread on Xylene substitutes.  It is comprised of isoalkenes, and is used in the histology industry.  I think the name is a little deceptive however.  It is used as a clearing agent to clear and remove parrafin from histology slides during the staining process, which xylene was the solvent of choice for many years.  Xylene subsitute as far as I know only replaces xylene in the histology industry.  I do not believe it can replace xylene in any other applications however.  I am not a chemist, though.  I know I can get the MSDS tommorow, I will get it to y'all....


  • Guest
Ha found it already
« Reply #3 on: July 08, 2003, 05:48:00 AM »
Sorry, in my first post I stated isoalkenes, I meant isoalkanes.  Anyway here is the MSDS.... I will leave it to the chemists to decide if this can actually be used as a xylene sub in clandestine chemistry.  Good luck....

1. Identification of the substance/preparation and of the company

Trade name
HistoSolve™, Xylene Substitute

Thermo Shandon, Inc.

171 Industry Drive

Pittsburgh, PA 15275 USA



Phone:    412-788-1133

Fax:        412-788-1138

Emergency telephone

Chem-Tel, Inc. 1-800-255-3924


2. Composition/Information on ingredients


% w/w                                              CAS no.               Classification       Exposure limits

100%      Isoalkanes C9-12                 90622-57-4            R10 Xn;R65          -

3. Hazards identification

Particular information pertaining specific risk for human and environment:
Flammable and harmful hydrocarbons with long-term effects.


4. First-aid measures

If any symptoms occur: Seek medical advice. Show this Safety Data Sheet to a physician or emergency ward.

Eye contact
Flush with water or physiological salt water for 15 minutes. Remember to remove contact lenses. If irritation persists: seek medical advice. Continue flushing on the way.

Skin contact
Remove contaminated clothing and wash skin with water and mild soap. Flush 15 minutes with water. Rub the skin with a hand lotion.

Remove to fresh air. Keep at rest. If symptoms persists: seek medical advice. Administer oxygen or artificial respiration as needed.

Rinse mouth and drink plenty water. Do not provoke vomiting. If vomiting occurs, bend over and keep head down to avoid vomit in the lungs.

Flush with water until pain ceases.

5. Fire-fighting measures


Combustible liquid.

Extinguishing media - suitable

Use dry chemical or foam.

Extinguishing media - NOT suitable


Special risks in a fire situation

Application of water fog/spray will aid in keeping fire-exposed materials cool. In case of fire the product may form hazardous decomposition product such as oxides of carbon.

Protective equipment
When extinguishing fires use self-contained breathing apparatus.

Additional information
Remove containers if possible.


6. Accidental release measures

Personal precautions
Provide for sufficient ventilation/respiratory protection. See protective equipment listed in  section 8. Remove sources of ignition.

Environmental precautions
Do not empty into drains. If the product contaminates lakes, rivers or sewages, inform appropriate authorities in accordance with local regulations.

Methods for cleaning up/collecting
Sweep up with a non flammable absorbent material. Flush with water.

Further handling of spillage: see section 13.


7. Handling and storage

Safe handling
See section 8.

Safe storage
At room temperature and well ventilated and away from strong oxidizers. Keep container tightly closed when not in use. Store in a flammable liquid storage area.


8. Exposure controls and personal protection

Engineering measures (prevention of worker exposure)

Avoid breathing of vapors and contact with skin, eyes and clothes. Provide adequate ventilation. There shall be access to water. Wash with water and soap after work.

Flammable, do not use near fire or sparks. Do not smoke.

Exposure limits: See section 2.

Personal protective equipment
Eye protection:                 Wear safety goggles when risk of splashing.

Skin protection:                Use gloves of nitrile rubber.

Respiratory protection:    In case of badly ventilated areas use an approved mask with a gas filter: A when risk of inhaling vapours.


9. Physical and chemical properties

Appearance:                                    Clear colourless liquid

Odour:                                             Characteristic odour of hydrocarbons

pH:                                                   -

Boiling point (°C):                           154-177

Flash point (°C):                              38-40

Explosion limits (%):                      0.6 - 7

Self-ignition temperature (°C):       293

Density g/ml at 24°C:                      0.75

Solubility in water:                           Negligible


10. Stability and reactivity

Vapors can be ignited by a spark, a hot surface or a glow. Vapors are heavier than air and can travel along the ground to an ignition source and flash back to vapor source.

Conditions to avoid
Sources of ignition, such as heat, sparks, and flames.

Materials to avoid
Strong oxidizing agents.

Hazardous decomposition products
Combustion may produce oxides of carbon.


11. Toxicological information

Routes of exposure:         May be absorbed by inhalation and ingestion.

Acute toxicity:   

             Eyes                    Splashes and high concentrations of vapors may cause irritation with redness.

         Skin                     May cause irritation with redness.

              Inhalation            Inhalation of vapors in high concentrations may irritate mucous membranes and induce headache, nausea, vomiting, dizziness and unconcsiousness.

              Ingestion             May irritate the gastrointestinal tract and cause symptoms as mentioned under inhalation. Hydrocarbons are harmful and may cause lung damage if swallowed. Be aware that symptoms (dyspnea) can develop several hours after exposure.

Long term toxicity:

Prolonged or frequent exposure to vapors of VOC´s may result in damage on liver, kidneys, blood or central nervous system (brain damage).


Additional toxicological information
The product was classified in toxicological terms on the basis of the results of the calculation procedure outlined within General directive on Preparations (88/379/EEC).


12. Ecological information

The hydrocarbons are volatile and evaporate from the water surface. The hydrocarbons are inherently biodegradable according to OECD guidelines. Do not empty into waters or drains.


13. Disposal considerations

Disposal should be according to local, state or national legislation. Dispose of through authority facilities or pass to chemical disposal company.

EWC-code: 160503


14. Transport information

Road/Rail (ADR/RID)

ADR/RID             : Class: 3               Item No.: 31                        Letter: c

UN No.                : 3295

Proper Shipping Name: Hydrocarbons, liquid, n.o.s. (isoalkanes C9-12)

Sea (IMDG)

IMDG Class          : 3                                       IMDG Page No.    : 3352

UN No.                : 3295                                  MARPOL             : -

MFAG                  : 310                                    EmS                     : 3-07     

Pack. Group          : III


15. Regulatory information

Classification according to EEC directives

Danger symbol and danger designation: Harmful

Contains:                           Isoalkanes C9-12

Risk-phrases:                    R 10:       Flammable.

R 65:       Harmful: may cause lung damage if swallowed.

Safety-phrases:                  S 23:       Do not breathe vapour.

S 24:       Avoid contact with skin.

S 62:       If swallowed, do not induce vomiting : seek medical advice immediately and show this container or label.


EINECS no.:                     292-459-0

National regulations:        -


16. Other information


For research and analysis.

Restriction on application

Requirements concerning special training
No special training is anticipated, however, the user should be well instructed for the execution of his task, have knowledge of this Safety Data Sheet and normal training in the use of personal protective equipment.



Edition no.: 03

(Revision) Date: 1/15/01


  • Guest
Not so sure
« Reply #4 on: July 08, 2003, 05:59:00 AM »
There are several xylene substitutes. Main function is to remove parafins as you say. Seem to be 3 types:

1. limonenes (orange oil etc)
2. long chain aliphatics
3. propylene glycol ether

Not sure which this is. A free gallon though...(even a tiny US one)...not to be missed surely?